Clavulanic acid degradation in Streptomyces clavuligerus fed-batch cultivations

Biotechnology Progress

Volumn 18, Issue 3, 2002, Pages 451-457

  Roubos, Johannes A ^a   Krabben, Preben ^a   De Laat, Wim T A M ^a   Babuška, Robert ^a   Heijnen, Joseph J ^a  

^a DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CLAVULANIC ACID;

ARTICLE; BIOREMEDIATION; CULTURE MEDIUM; FERMENTATION; METABOLISM; STREPTOMYCES;

BIODEGRADATION, ENVIRONMENTAL; CLAVULANIC ACID; CULTURE MEDIA; FERMENTATION; STREPTOMYCES; BIODEGRADATION; SUPPORT, NON-U.S. GOV'T;

EXPONENTIAL GROWTH;

AMMONIUM COMPOUNDS; BATCH CELL CULTURE; BIODEGRADATION; ESTERS; FUZZY SETS; GLYCEROL; MICROORGANISMS; PHOSPHATES; RATE CONSTANTS;

ANTIBIOTICS;

STREPTOMYCES; STREPTOMYCES CLAVULIGERUS;

EID: 0035988006     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp020294n     Document Type: Article

References (19)

1. Manipulation of the physiology of clavulanic acid production in Streptomyces clavuligerus
2. Simultaneous production and decomposition of clavulanic acid during Streptomyces clavuligerus cultivations
3. Improvement of clavulanic acid production by streptomyces clavuligerus in medium containing soybean derivatives
4. Chemistry and biosynthesis of clavulanic acid and other clavams
5. Stability of clavulanic acid in aqueous solutions
6. The disposition of clavulanic acid in man
7. Studies on the hydrolysis of clavulanic acid
8. The chemistry of clavulanic acid: Some reactions of esters under neutral, acedic and basic conditions
9. A semi-stoichiometric model for a Streptomyces fed-batch cultivation with multiple feeds
10. Spectrophotometric assay of clavulanic acid by reaction with imidazole
11. Spectrophotometric determination of ammonia: A study of a modified berthelot reaction using salicylate and dichloroisocyanurate
12. A quantitative approach to characterizing cell lysis caused by mechanical agitation of Streptomyces clavuligerus
13. Fuzzy identification of systems and its application to modeling and control
14. GA-fuzzy modeling and classification: Complexity and performance
15. Computer modeling of antibiotic fermentation with on-line product removal