Ikaros: A key regulator of haematopoiesis

International Journal of Biochemistry and Cell Biology

Volumn 34, Issue 10, 2002, Pages 1304-1307

  Westman, Belinda J ^a   Mackay, Joel P ^a   Gell, David ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Haematopoiesis; Ikaros; Pericentromeric heterochromatin; Transcription

Indexed keywords

ADENOSINE TRIPHOSPHATE; HISTONE ACETYLTRANSFERASE; IKAROS TRANSCRIPTION FACTOR; NUCLEAR FACTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; DNA BINDING PROTEIN;

ACCURACY; ARTICLE; B LYMPHOCYTE; CELL DIFFERENTIATION; CELL MATURATION; CELL NUCLEUS; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CHROMATIN; HEMATOPOIESIS; LYMPHOCYTE; LYMPHOID CELL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; T LYMPHOCYTE; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; ANIMAL; CHEMISTRY; GENETICS; PHYSIOLOGY; PROTEIN CONFORMATION; REVIEW;

ANIMAL; HEMATOPOIESIS; PROTEIN CONFORMATION; SUPPORT, NON-U.S. GOV'T; TRANSCRIPTION FACTORS; ANIMALS; DNA-BINDING PROTEINS; IKAROS TRANSCRIPTION FACTOR;

EID: 0035986647     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-2725(02)00070-5     Document Type: Article

References (14)

1. Ikaros: An early lymphoid-specific transcription factor and a putative mediator for T-cell commitment
2. Cloning and sequencing of hIk-1, a cDNA encoding a human homologue of mouse Ikaros/LyF-1
3. Haematopoietic cell-fate decisions, chromatin regulation and Ikaros
4. The role of the Ikaros gene in lymphocyte development and homeostasis
5. The Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteins
6. Multiple hematopoietic defects and delayed globin switching in Ikaros null mice
7. Regulation of L-selectin expression by a dominant negative Ikaros protein
8. An intronic Ikaros-binding element mediates retinoic acid suppression of the kappa opioid receptor gene, accompanied by histone deacetylation on the promoters
9. Genomic organization and expression of the human tumorous imaginal disc (TID1) gene
10. AP-2 and Ikaros regulate transcription of human placental leucine aminopeptidase/oxytocinase gene
11. Unconventional potentiation of gene expression by Ikaros
12. Expression of dominant-negative and mutant isoforms of the antileukemic transcription factor Ikaros in infant acute lymphoblastic leukemia
13. Expression of dominant-negative Ikaros isoforms in T-cell acute lymphoblastic leukemia
14. Decreases in Ikaros activity correlate with blast crisis in patients with chronic myelogenous leukemia