Ku antigen supports termination of mammalian rDNA replication by transcription termination factor TTF-I

Biological Chemistry

Volumn 383, Issue 5, 2002, Pages 765-771

  Wallisch, Michael ^a   Kunkel, Elisabeth ^a   Hoehn, Karsten ^a   Grummt, Friedrich ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Ku antigen; Replication fork barrier; Replication termination; Transcription termination factor I

Indexed keywords

AUTOANTIBODY; CELL EXTRACT; CELL NUCLEUS DNA; CYTOSINE; DNA BINDING PROTEIN; GUANINE; KU ANTIGEN; POLYPEPTIDE; RIBOSOME DNA; RIBOSOME RNA; TRANSCRIPTION TERMINATION FACTOR RHO; CELL NUCLEUS ANTIGEN; HELICASE; NUCLEAR PROTEIN; OLIGODEOXYRIBONUCLEOTIDE; PROTEIN SUBUNIT; RECOMBINANT PROTEIN; TTF1 PROTEIN, HUMAN; TTF1 PROTEIN, MOUSE; XRCC5 PROTEIN, HUMAN;

ARTICLE; AUTOIMMUNE DISEASE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DNA PROTEIN COMPLEX; DNA REPLICATION; ELECTROPHORETIC MOBILITY; GENETIC TRANSCRIPTION; HELA CELL; HUMAN; HUMAN CELL; INSECT CELL; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; ANIMAL; BIOSYNTHESIS; CELL LINE; DNA REPLICATION ORIGIN; ENZYME SPECIFICITY; INSECT; METABOLISM; MOLECULAR GENETICS; MOUSE; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROTEIN BINDING;

ANIMAL; BASE SEQUENCE; BINDING SITES; CELL LINE; DNA REPLICATION; DNA, RIBOSOMAL; DNA-BINDING PROTEINS; HELA CELLS; HUMAN; INSECTS; MICE; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; OLIGODEOXYRIBONUCLEOTIDES; PROTEIN BINDING; PROTEIN SUBUNITS; RECOMBINANT PROTEINS; REPLICATION ORIGIN; SUBSTRATE SPECIFICITY; SUPPORT, NON-U.S. GOV'T; ANIMALS; ANTIGENS, NUCLEAR; DNA HELICASES; HUMANS;

INSECTA; MAMMALIA;

EID: 0035985059     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/BC.2002.080     Document Type: Article

References (26)

1. A replication fork barrier at the 3 end of yeast ribosomal RNA genes
2. The arrest of replication forks in the rDNA of yeast occurs independently of transcription
3. Ku, a DNA repair protein with multiple cellular functions?
4. Termination of mammalian rDNA replication: Polar arrest of replication fork movement by transcription termination factor TTF-I
5. Sequence-specific DNA binding by Ku autoantigen and its effects on transcription
6. Transcription of mouse rDNA terminates downstream of the 3' end of 28S RNA and involves interaction of factors with repeated sequences in the 3' spacer
7. A repeated 18 bp sequence motif in the mouse rDNA spacer mediates binding of nuclear factor and transcription termination
8. Conserved features in the mode of replication of eukaryotic ribosomal RNA genes
9. Altered phosphorylation pattern of simian virus 40 T antigen expressed in insect cells by using a baculovirus vector
10. Natural point mutations within rat rDNA transcription terminator elements reveal the functional importance of single bases for factor binding and termination
11. Identification of a site required for DNA replication fork blocking activity in the rRNA gene cluster in Saccharomyces cerevisiae
12. The mouse ribosomal gene terminator consists of three functionally separable sequence elements
13. Organization of replication of ribosomal DNA in Saccharomyces cerevisiae
14. Initiation and termination of DNA replication in human rRNA genes
15. Co-localization of polar replication fork barriers and rRNA transcription terminators in mouse rDNA
16. Characterization of the pea rDNA replication for barrier: Putative cis-acting and trans-acting factors
17. Chromatin structure and transcriptional activity around the replication forks arrested at the 3'end of the yeast rRNA genes
18. Mechanism of interaction between Ku protein and DNA
19. Characterization of the DNA-binding protein antigen Ku recognized by autoantibodies from patients with rheumatic disorders
20. Production and characterization of recombinant human Ku antigen
21. An undecamer DNA sequence directs termination of human ribosomal gene transcription
22. Use of monoclonal antibodies for the characterization of novel DNA-binding proteins recognized by human autoimmune sera
23. Ribosomal DNA replication in the fission yeast, Schizosaccharomyces pombe
24. Replication fork barriers in the Xenopus rDNA
25. In vitro replication of duplex circular DNA containing the simian virus 40 DNA origin site
26. Purification of an 86-70 kDa nuclear DNA-associated protein complex