Distinct but overlapping domains of AKAP95 are implicated in chromosome condensation and condensin targeting

EMBO Reports

Volumn 3, Issue 5, 2002, Pages 426-432

  Eide, Turid ^a   Carlson, Catherine ^a   Taskén, Kristin A ^a   Hirano, Tatsuya ^b   Taskén, Kjetil ^c   Collas, Philippe ^d  

^a DIVISION OF REPRODUCTIVE BIOLOGY   (United States)

^b UNIVERSITY OF LONDON   (United Kingdom)

^c RESEARCH AND DEVELOPMENT   (Australia)

^d UNIVERSITY OF OSLO   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; AKAP8L PROTEIN, HUMAN; CONDENSIN COMPLEXES; DNA BINDING PROTEIN; MULTIPROTEIN COMPLEX; NUCLEAR PROTEIN; RECOMBINANT PROTEIN; SIGNAL PEPTIDE; CONDENSIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; MUTANT PROTEIN; PROTEIN AKAP95; PROTEIN SUBUNIT; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ANIMAL; ARTICLE; CHROMOSOME; GENE DELETION; GENETICS; HELA CELL; HUMAN; METABOLISM; MUTATION; PROTEIN TERTIARY STRUCTURE; SEQUENCE ANALYSIS; XENOPUS; CARBOXY TERMINAL SEQUENCE; CHROMATIN CONDENSATION; CHROMOSOME CONDENSATION; COMPLEX FORMATION; CONTROLLED STUDY; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MITOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN TARGETING;

ADENOSINE TRIPHOSPHATASES; ANIMALS; CHROMOSOMES; DNA-BINDING PROTEINS; HELA CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MULTIPROTEIN COMPLEXES; MUTATION; NUCLEAR PROTEINS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SEQUENCE ANALYSIS, PROTEIN; SEQUENCE DELETION; XENOPUS; ADENOSINETRIPHOSPHATASE; ANIMAL; HUMAN; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0035984895     PISSN: 1469221X     EISSN: None     Source Type: Journal    
DOI: 10.1093/embo-reports/kvf089     Document Type: Article

References (19)

1. A-kinase-anchoring protein AKAP95 is targeted to the nuclear matrix and associates with p68 RNA helicase
2. Chromatid segregation at anaphase requires the Barren product, a novel chromosome associated protein that binds topoisomerase II
3. Association of the type II cAMP-dependent protein kinase with a human thyroid RII-anchoring protein. Cloning and characterization of the RII-binding domain
4. Cloning and characterization of AKAP95, a nuclear protein that associates with the regulatory subunit of type II cAMP-dependent protein kinase
5. The A-kinase anchoring protein, AKAP95, is a multivalent protein with a key role in chromatin condensation at mitosis
6. Molecular cloning, chromosomal localization, and cell cycle-dependent subcellular distribution of the A-kinase anchoring protein, AKAP95
7. The biological functions of A-kinase anchor proteins
8. Chromosome cohesion, condensation, and separation
9. Condensins, chromosome condensation protein complexes containing XCAP-C, XCAP-E and a Xenopus homolog of the Drosophila Barren protein
10. ATP-dependent positive supercoiling of DNA by 13S condensin: A biochemical implication for chromosome condensation
11. Dual roles of the 11S regulatory subcomplex in condensin functions
12. Phosphorylation and activation of 13S condensin by Cdc2 in vitro
13. 13S condensin actively reconfigures DNA by introducing global positive writhe: Implications for chromosome condensation
14. Chromosome condensation by a human condensin complex in Xenopus egg extracts
15. HEAT repeats associated with condensins, cohesins, and other complexes involved in chromosome-related functions
16. Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics
17. A human condensin complex containing hCAP-C-hCAP-E and CNAP1, a homolog of Xenopus XCAP-D2, colocalizes with phosphorylated histone H3 during the early stage of mitotic chromosome condensation
18. A-kinase anchoring protein (AKAP)95 recruits human chromosome-associated protein (hCAP)-D2/Eg7 for chromosome condensation in mitotic extract
19. Histone H3 phosphorylation is required for the initiation, but not maintenance, of mammalian chromosome condensation