Inactivation of the Streptococcus mutans fxpC gene confers resistance to xylitol, a caries-preventive natural carbohydrate sweetener

Journal of Dental Research

Volumn 81, Issue 6, 2002, Pages 380-386

  Benchabane, H ^a   Lortie, L A ^a   Buckley, N D ^a   Trahan, L ^a   Frenette, Michel ^a  

^a UNIVERSITÉ LAVAL   (Canada)

Author keywords

Caries prevention; Dental caries; Oral streptococci

Indexed keywords

BACTERIAL PROTEIN; FIMBRIA PROTEIN; MEMBRANE PROTEIN; PHOSPHOENOLPYRUVATE SUGAR PHOSPHOTRANSFERASE; XYLITOL;

AMINO ACID SEQUENCE; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIUM TRANSFORMATION; CHROMOSOME WALKING; ENZYMOLOGY; GENE SILENCING; GENETIC TRANSCRIPTION; GENETICS; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; OPERON; PHYSIOLOGY; POLYMERASE CHAIN REACTION; STREPTOCOCCUS MUTANS;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BASE SEQUENCE; CHROMOSOME WALKING; DRUG RESISTANCE, BACTERIAL; FIMBRIAE PROTEINS; GENE SILENCING; GENES, BACTERIAL; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; OPERON; PHOSPHOENOLPYRUVATE SUGAR PHOSPHOTRANSFERASE SYSTEM; POLYMERASE CHAIN REACTION; STREPTOCOCCUS MUTANS; TRANSCRIPTION, GENETIC; TRANSFORMATION, BACTERIAL; XYLITOL;

EID: 0035983375     PISSN: 00220345     EISSN: None     Source Type: Journal    
DOI: 10.1177/0810380     Document Type: Article

References (30)

1. Cloning, sequence, and expression of the phosphofructokinase gene of Clostridium acetobutylicum ATCC824 in Escherichia coli
2. Use of a novel mobilizable vector to inactivate the ScrA gene of Streptococcus sobrinus by allelic replacement
3. An effective strategy applicable to Streptococcus salivarius and related bacteria, to enhance or confer electrocompetence
4. Fructose catabolism in Xanthomonas campestris pv Campestris
5. A comprehensive set of sequence analysis programs for the VAX
6. Isolation of a novel protein involved in the transport of fructose by an inducible phosphoenolpyruvate fructose phosphotransferase system in Streptococcus mutans
7. Catabolite repression in Bacillus subtilis: A global regulatory mechanism for the Gram-positive bacteria?
8. Effect of xylitol on growth of nasopharyngeal bacteria in vitro
9. Enzymes II of the phosphoenolpyruvate-dependent phosphotransferase systems: Their structure and function in carbohydrate transport
10. The rationale for caries prevention through the use of sugar substitutes
11. IS1139 from Streptococcus salivarius: Identification and characterization of an insertion sequence-like element related to mobile DNA elements from Gram-negative bacteria
12. Purification and characterization of the deoR repressor of Escherichia coli
13. Cloning and characterization of a gene cluster from Bacillus stearothermophilus comprising infC, rpmI and rplT
14. Phosphoenolpyruvate: Carbohydrate phosphotransferase systems of bacteria
15. Sequence of the fruB gene of Escherichia coli encoding the diphosphoryl transfer protein (DTP) of the phosphoenolpyruvate: Sugar phosphotransferase system
16. Novel phosphotransferase system genes revealed by bacterial genome analysis - A gene cluster encoding a unique enzyme I and the proteins of a fructose-like permease system
17. Nucleotide and deduced amino acid sequences of the lacR, lacABCD, and lacFE genes encoding the repressor, tagatose 6-phosphate gene cluster, and sugar-specific phosphotransferase system components of the lactose operon of Streptococcus mutans
18. Regulation of glycerol metabolism in Pseudomonas aeruginosa: Characterization of the glpR repressor gene
19. Xylitol chewing gum and dental caries
20. Xylitol: A review of its action on mutans streptococci and dental plaque - Its clinical significance
21. Transport and phosphorylation of xylitol by a fructose phosphotransferase system in Streptococcus mutans
22. Emergence of xylitol-resistant (Frucose PTS) mutants from human isolates of mutans streptococci during growth on dietary sugars in the presence of xylitol
23. Xylitol chewing gum in prevention of acute otitis media: Double blind randomised trial
24. Comparative study of Streptococcus mutans laboratory stains and fresh isolates from carious and caries-free tooth surfaces from subjects with hereditary fructose intolerance
25. Role of micro-organisms in caries etiology
26. Site-directed mutagenesis of a catabolite repression operator sequence in Bacillus subtilis
27. Characterization of two operons that encode components of fructose-specific enzyme II of the sugar:phosphotransferase system of Streptococcus mutans
28. Regulation of sugar uptake via the phosphoenolpyruvate-dependent phosphotransferase systems in Bacillus subtilis and Lactococcus lactis is mediated by ATP-dependent phosphorylation of seryl residue 46 in HPr