In vivo evaluation of 99mTc-DTPA and 99mTc-sulphur colloid as tracers in colonic drug delivery systems using gamma scintigraphy in volunteers

Journal of Pharmacy and Pharmaceutical Sciences

Volumn 5, Issue 1, 2002, Pages 24-28

  Krishnaiah, Y S R ^a   Satyanarayana, S ^a   Rama Prasad, Y V ^a   Narasimha Rao, S ^a  

^a ANDHRA UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME; GUAR GUM; MAGNESIUM STEARATE; MICROCRYSTALLINE CELLULOSE; PENTETATE TECHNETIUM TC 99M; SODIUM CHLORIDE; TECHNETIUM SULFUR COLLOID TC 99M; TRACER; WATER; RADIOPHARMACEUTICAL AGENT;

ARTICLE; COLON; CONTROLLED STUDY; DIFFUSION; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG SCREENING; DRUG SOLUBILITY; ENZYMATIC DEGRADATION; GAMMA SCINTIGRAPHY; IN VIVO STUDY; ISOTOPE LABELING; SMALL INTESTINE; STOMACH; TABLET COMPRESSION; TABLET DISINTEGRATION TIME; VOLUNTEER; ADULT; GAMMA RADIATION; HUMAN; MALE; PROCEDURES; SCINTISCANNING;

ADULT; COLON; DRUG DELIVERY SYSTEMS; DRUG EVALUATION; GAMMA RAYS; HUMANS; MALE; RADIOACTIVE TRACERS; RADIOPHARMACEUTICALS; TECHNETIUM TC 99M PENTETATE; TECHNETIUM TC 99M SULFUR COLLOID;

EID: 0035983157     PISSN: 14821826     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Gastric emptying and small and large bowel transit of non-disintegrating tablets in fasted volunteers
2. The gastrointestinal transit and systemic absorption of diltiazem HCl from a modified-release dosage form
3. Imaging and behaviour of solid oral dosage forms in vivo
4. The role of gamma scintigraphy in oral drug delivery
5. An in vivo investigation into the suitability of pH dependent polymers for colon targeting
6. An evaluation of pectin as a carrier for drug targeting to the colon
7. Colonic delivery of dexamethasone: A pharmacoscintigraphic evaluation
8. Gastrointestinal transit of small tablets in patients with ulcerative colitis
9. Pharmacoscintigraphic evaluation of oral delivery systems
10. The fermentability of polysaccharides by mixed human fecal bacteria in relation to their suitability as bulk-forming laxatives
11. Gamma scintigraphic studies on guar gum matrix tablets for colonic drug delivery in healthy volunteers
12. Evaluation of guar gum as a compression coat for drug targeting to colon
13. In Vitro evaluation of guar gum as a carrier for colon-specific drug delivery
14. Tablet Dosage Forms