A novel polymorphism, 70Leu/Phe, disrupts a consensus Leu residue within the leucine-rich repeat sequence of platelet glycoprotein Ibα

Thrombosis and Haemostasis

Volumn 87, Issue 5, 2002, Pages 867-872

  Matsubara, Yumiko ^a   Murata, Mitsuru ^a   Moriki, Takanori ^a   Yokoyama, Kenji ^a   Watanabe, Naohide ^a   Nakajima, Hideaki ^a   Handa, Makoto ^a   Kawano, Koichi ^a   Aoki, Nobuo ^a   Yoshino, Hideaki ^a   Ikeda, Yasuo ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

Genetics; Glycoprotein Ib ; Leucine rich repeat; Platelets; Polymorphism

Indexed keywords

ALPHA1 GLYCOPROTEIN; GLYCOPROTEIN IB; LEUCINE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY GUR20 5; MONOCLONAL ANTIBODY HIP1; PHENYLALANINE; RISTOCETIN; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR; EPITOPE; HYBRID PROTEIN; PEPTIDE FRAGMENT; PROTEIN SUBUNIT; THROMBIN RECEPTOR;

ADULT; AMINO ACID ANALYSIS; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHINESE HAMSTER; CONFORMATION; CONTROLLED STUDY; EPITOPE MAPPING; GENOTYPE; HUMAN; HUMAN EXPERIMENT; IN VITRO STUDY; JAPAN; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; PROTEIN STRUCTURE; SEQUENCE ANALYSIS; SHEAR STRESS; SIMPLE SEQUENCE REPEAT; THROMBOCYTE AGGREGATION; THROMBOCYTE RICH PLASMA; AMINO ACID SEQUENCE; ANIMAL; ANTIBODY SPECIFICITY; ASIAN; CHEMISTRY; CHO CELL; CONSENSUS SEQUENCE; CRICETULUS; DRUG EFFECT; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETICS; HAMSTER; IMMUNOLOGY; MISSENSE MUTATION; POINT MUTATION; PROTEIN CONFORMATION; THROMBOCYTE;

AMINO ACID SUBSTITUTION; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; ASIAN CONTINENTAL ANCESTRY GROUP; BLOOD PLATELETS; CHO CELLS; CONSENSUS SEQUENCE; CRICETINAE; CRICETULUS; EPITOPES; GENE FREQUENCY; GENOTYPE; HUMANS; JAPAN; LEUCINE; MUTATION, MISSENSE; PEPTIDE FRAGMENTS; PLATELET AGGREGATION; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; POINT MUTATION; POLYMORPHISM, GENETIC; PROTEIN CONFORMATION; PROTEIN SUBUNITS; RECOMBINANT FUSION PROTEINS; REPETITIVE SEQUENCES, AMINO ACID; RISTOCETIN;

EID: 0035983139     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1613098     Document Type: Article

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