Antibody penetration into a spherical prevascular tumor nodule embedded in normal tissue

Annals of Biomedical Engineering

Volumn 30, Issue 6, 2002, Pages 828-839

  Banerjee, Rupak K ^a   Sung, Cynthia ^b   Bungay, Peter M ^a   Dedrick, Robert L ^a   Van Osdol, William W ^c  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b GLAXOSMITHKLINE   (United States)

^c ALZA CORPORATION   (United States)

Author keywords

Diffusion; Finite element mathematical model; Monoclonal antibody; Pharmacokinetics; Tumor antigen

Indexed keywords

APPROXIMATION THEORY; DIFFUSION; FINITE ELEMENT METHOD; MATHEMATICAL MODELS; MONOCLONAL ANTIBODIES; PHARMACOKINETICS; SENSITIVITY ANALYSIS;

PREVASCULAR TUMORS;

TUMORS;

DIAGNOSTIC AGENT; MONOCLONAL ANTIBODY; RADIOPHARMACEUTICAL AGENT; TUMOR ANTIGEN;

ANIMAL; ANTIBODY AFFINITY; ARTICLE; BIOLOGICAL MODEL; BLOOD; COMPARATIVE STUDY; COMPUTER SIMULATION; DIFFUSION; FINITE ELEMENT ANALYSIS; HUMAN; IMMUNOLOGY; METABOLISM; NEOPLASM; REPRODUCIBILITY; SCINTISCANNING; SENSITIVITY AND SPECIFICITY; TISSUE DISTRIBUTION; VASCULARIZATION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY AFFINITY; ANTIGENS, NEOPLASM; COMPUTER SIMULATION; DIFFUSION; FINITE ELEMENT ANALYSIS; HUMANS; MODELS, BIOLOGICAL; NEOPLASMS; RADIOPHARMACEUTICALS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TISSUE DISTRIBUTION;

EID: 0035982812     PISSN: 00906964     EISSN: None     Source Type: Journal    
DOI: 10.1114/1.1496087     Document Type: Article

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