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Volumn 123, Issue 43, 2001, Pages 10429-10435
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Rational design of diflunisal analogues with reduced affinity for human serum albumin
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Author keywords
[No Author keywords available]
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Indexed keywords
ALBUMIN BINDING;
CARBOXYLIC ACIDS;
NUCLEAR MAGNETIC RESONANCE;
PROTEINS;
X RAY ANALYSIS;
LEAD COMPOUNDS;
ANTIINFLAMMATORY AGENT;
CARBOXYLIC ACID;
CYCLOOXYGENASE 2;
CYCLOOXYGENASE 2 INHIBITOR;
DIFLUNISAL;
DIFLUNISAL DERIVATIVE;
HUMAN SERUM ALBUMIN;
MYRISTIC ACID;
UNCLASSIFIED DRUG;
ARTICLE;
BINDING AFFINITY;
BINDING SITE;
CONTROLLED STUDY;
CRYSTAL STRUCTURE;
DRUG DESIGN;
DRUG PROTEIN BINDING;
DRUG STRUCTURE;
DRUG SYNTHESIS;
ELECTRICITY;
ENZYME INHIBITION;
MOLECULAR INTERACTION;
NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;
PROTEIN DOMAIN;
STRUCTURE ACTIVITY RELATION;
STRUCTURE ANALYSIS;
X RAY CRYSTALLOGRAPHY;
AMINO ACID SEQUENCE;
ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL;
BINDING SITES;
CRYSTALLOGRAPHY, X-RAY;
DIFLUNISAL;
DRUG DESIGN;
HUMANS;
KINETICS;
MOLECULAR SEQUENCE DATA;
NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR;
PROTEIN CONFORMATION;
SERUM ALBUMIN;
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EID: 0035980337
PISSN: 00027863
EISSN: None
Source Type: Journal
DOI: 10.1021/ja015955b Document Type: Article |
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Times cited : (96)
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References (28)
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