Dissociation of Heparan Sulfate and Receptor Binding Domains of Hepatocyte Growth Factor Reveals that Heparan Sulfate-c-Met Interaction Facilitates Signaling

Journal of Biological Chemistry

Volumn 276, Issue 35, 2001, Pages 32977-32983

  Rubin, Jeffrey S ^a   Day, Regina M ^a   Breckenridge, Diane ^a   Atabey, Nese ^a   Taylor, William G ^a   Stahl, Stephen J ^b   Wingfield, Paul T ^b   Kaufman, Joshua D ^b   Schwall, Ralph ^c   Bottaro, Donald P ^a,d  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^c GENENTECH INC   (United States)

^d ENTREMED INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DISSOCIATION; PROTEINS; SOLUBILITY; SULFUR COMPOUNDS;

HEPATOCYTE GROWTH FACTOR (HGF);

BIOCHEMISTRY;

BINDING PROTEIN; FIBROBLAST GROWTH FACTOR; GLYCOSAMINOGLYCAN; HEPARAN SULFATE; HEPARIN; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE; ONCOPROTEIN; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; UNCLASSIFIED DRUG; DNA; ISOPROTEIN; PEPTIDE FRAGMENT;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL MOTILITY; CELL SURFACE; CONTROLLED STUDY; DISSOCIATION; ENDOTHELIUM CELL; ENZYME ACTIVATION; EPITHELIUM CELL; HEMATOPOIETIC CELL; KRINGLE DOMAIN; LIVER CELL; MELANOCYTE; MITOGENESIS; MORPHOGENESIS; MOUSE; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; SIGNAL TRANSDUCTION; ANIMAL; BAGG ALBINO MOUSE; BINDING SITE; BIOSYNTHESIS; CELL CULTURE; CELL DIVISION; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; CYTOLOGY; DOG; DRUG EFFECT; ISOLATION AND PURIFICATION; KERATINOCYTE; KIDNEY; METABOLISM; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE;

ANIMALIA;

ANIMALS; BINDING SITES; CELL DIVISION; CELL LINE; CELLS, CULTURED; DNA; DOGS; HEPARITIN SULFATE; HEPATOCYTE GROWTH FACTOR; KERATINOCYTES; KIDNEY; MICE; MICE, INBRED BALB C; MODELS, MOLECULAR; PEPTIDE FRAGMENTS; PROTEIN ISOFORMS; PROTEIN STRUCTURE, SECONDARY; PROTO-ONCOGENE PROTEINS C-MET; SIGNAL TRANSDUCTION;

EID: 0035980123     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M105486200     Document Type: Article

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