Application of sorption-desorption moisture transfer modeling to the study of chemical stability of a moisture sensitive drug product in different packaging configurations

International Journal of Pharmaceutics

Volumn 223, Issue 1-2, 2001, Pages 1-13

  Badawy, Sherif I Farag ^a   Gawronski, Anthony J ^a   Alvarez, Francisco J ^a  

^a DUPONT COMPANY   (United States)

Author keywords

Desorption; Humidity; Moisture; Packaging; Sorption; Stability

Indexed keywords

DESICCANT; POLYETHYLENE; ROXIFIBAN;

ARTICLE; CORRELATION FUNCTION; DESORPTION; DRUG ABSORPTION; DRUG DEGRADATION; DRUG EFFECT; DRUG MANUFACTURE; DRUG STABILITY; HUMIDITY; PRIORITY JOURNAL; TABLET; WEIGHT;

ADSORPTION; DRUG PACKAGING; DRUG STABILITY; HUMIDITY; TABLETS;

EID: 0035979420     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(01)00693-7     Document Type: Article

References (6)

1. Chemical stability of an ester prodrug of a glycoprotein IIb/IIIa receptor antagonist in solid dosage forms
2. Distribution of water in solid pharmaceutical systems
3. Gelatin capsule brittleness as a function of relative humidity at room temperature
4. Use of the sorption-desorption moisture transfer model to assess the utility of a desiccant in a solid product
5. The interaction of water with cellulose- and starch-derived pharmaceutical excipients
6. Prediction of moisture transfer in mixtures of solids: Transfer via the vapor phase