Asymmetric synthesis of [2,3-13C2,15N]-4-benzyloxy-5,6-diphenyl-2, 3,5,6-tetrahydro-4H-oxazine-2-one via lipase TL-mediated kinetic resolution of benzoin: General procedure for the synthesis of [2,3-13C2,15N]-L-alanine

Journal of Organic Chemistry

Volumn 66, Issue 24, 2001, Pages 8010-8014

  Aoyagi, Yutaka ^a   Iijima, Ai ^a   Williams, Robert M ^b  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^b Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIMERIZATION;

ALKYLATION; HYDROGENATION; HYDROLYSIS; SYNTHESIS (CHEMICAL);

AROMATIC COMPOUNDS;

2 AMINO 1,2 DIPHENYLETHANOL DERIVATIVE; 4 BENZYLOXY 5,6 DIPHENYL 2,3,5,6 TETRAHYDRO 4H OXAZIN 2 ONE; ALANINE DERIVATIVE; BENZOIN; BENZOIN O ACETATE; BROMOACETIC ACID; CARBON 13; NITROGEN 15; OXAZINE DERIVATIVE; PHENETHYL ALCOHOL; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CHEMICAL REACTION; CHEMICAL REACTION KINETICS; ENANTIOMER; HYDROGENATION; HYDROLYSIS; REACTION ANALYSIS; SYNTHESIS;

ALANINE; BENZOIN; CARBON RADIOISOTOPES; ISOTOPE LABELING; LIPASE; NITROGEN ISOTOPES; OXAZINES; STEREOISOMERISM;

EID: 0035977263     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo015725f     Document Type: Article

References (62)

1. Synthesis of optically active α-amino acids
2. Hydrolytic reactions