Specific inhibition of a family 1A dihydroorotate dehydrogenase by benzoate pyrimidine analogues

Journal of Medicinal Chemistry

Volumn 44, Issue 18, 2001, Pages 2861-2864

  Palfey, B A ^a   Bjornberg O ^b   Jensen, K F ^b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOIC ACID; DIHYDROOROTATE DEHYDROGENASE; HYDROXYBENZOIC ACID; PYRIMIDINE DERIVATIVE;

ARTICLE; BINDING AFFINITY; CATALYSIS; COMPETITIVE INHIBITION; DISSOCIATION CONSTANT; ENZYME INHIBITION; ENZYME MECHANISM; LACTOCOCCUS LACTIS; LIGAND BINDING; PROTON TRANSPORT; X RAY DIFFRACTION;

BENZOATES; DIHYDROOROTATE OXIDASE; ENZYME INHIBITORS; LIGANDS; PYRIMIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOCIDAL AGENTS;

EID: 0035974643     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm015535x     Document Type: Article

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