Cloning and functional characterization of the human heterogeneous nuclear ribonucleoprotein type I promoter

Biochimica et Biophysica Acta - Gene Structure and Expression

Volumn 1520, Issue 1, 2001, Pages 85-88

  Romanelli, Maria Grazia ^a   Faggioli, Laura ^a   Lorenzi, Pamela ^a   Morandi, Carlo ^a  

^a UNIVERSITY OF VERONA   (Italy)

Author keywords

Chloramphenicol acetyltransferase reporter assay; Heterogeneous nuclear ribonucleoprotein type I; Polypyrimidine tract binding protein; Promoter activity; Transcription

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; COMPLEMENTARY DNA; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN TYPE 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NF1; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ARTICLE; BINDING SITE; CONTROLLED STUDY; DNA FLANKING REGION; DNA SEQUENCE; GC RICH SEQUENCE; GENE AMPLIFICATION; GENE CONSTRUCT; GENE DELETION; GENE EXPRESSION; HELA CELL; HUMAN; HUMAN CELL; MOLECULAR CLONING; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REPORTER GENE; SEQUENCE ANALYSIS; TATA BOX; TRANSCRIPTION INITIATION;

BASE SEQUENCE; CHLORAMPHENICOL O-ACETYLTRANSFERASE; CLONING, MOLECULAR; GENES, REPORTER; HELA CELLS; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEINS; HUMANS; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); RIBONUCLEOPROTEINS;

EID: 0035973849     PISSN: 01674781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4781(01)00259-7     Document Type: Article

References (24)

1. Identification and purification of a 62,000-dalton protein that binds specifically to the polypyrimidine tract of introns
2. Characterization of cDNAs encoding the polypyrimidine tract-binding protein
3. HnRNP I, the polypyrimidine tract-binding protein: Distinct nuclear localization and association with hnRNAs
4. HnRNP proteins and the biogenesis of mRNA
5. The roles of heterogeneous nuclear ribonucleoproteins (hnRNP) in RNA metabolism
6. HnRNP complexes: Composition, structure, and function
7. Polypyrimidine tract binding protein interacts with sequences involved in alternative splicing of beta-tropomyosin pre-mRNA
8. A neuron-specific splicing switch mediated by an array of pre-mRNA repressor site: Evidence of a regulatory role for the polypyrimidine tract binding protein and a brain-specific PTB counterpart
9. The polypyrimidine tract binding protein binds upstream of neural cell-specific c-src exon N1 to repress the splicing of the intron downstream
10. Mutation of the PTB binding sites causes misregulation of alternative 3′ splice site selection in vivo
11. Role of an inhibitory element and pyrimidine tract binding protein in repression of a regulated a-tropomyosin exon
12. Post-transcriptional regulation: The dawn of PTB
13. Alternative splicing of pre-mRNA: Developmental consequences and mechanisms of regulation
14. The use of antibodies to the polypyrimidine tract binding protein (PTB) to analyze the protein components that assemble an alternatively spliced pre-mRNAs that use distant branch points
15. Coordinate repression of a trio of neuron-specific splicing events by the splicing regulator PTB
16. Characterization and molecular cloning of polypyrimidine tract-binding protein: A component of a complex necessary for pre-mRNA splicing
17. Dual localization of the human gene encoding hnRNP I/PTB protein to chromosome 19p13.3 and 14q23
18. Organization of the human gene encoding heterogeneous nuclear ribonucleoprotein type I (hnRNP I) and characterization of hnRNP I related pseudogene
19. A novel isoform ratio switch of the polypyrimidine tract binding protein
20. Fibroblast growth factor receptor-1 a-exon exclusion and polypyrimidine tract-binding protein glioblastoma multiform tumors
21. Rapid production of full-length cDNAs from rare transcripts: Amplification using a single gene-specific oligonucleotide primer
22. Transcription from TATA-less promoters: Dihydrofolate reductase as a model
23. YY1 is an initiator sequence-binding protein that directs and activates transcription in vitro
24. CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements