Effect of physico-chemical modification on the immunogenicity of Haemophilus influenzae type b oligosaccharide-CRM197 conjugate vaccines

Vaccine

Volumn 19, Issue 23-24, 2001, Pages 3189-3200

  Bolgiano, Barbara ^a   Mawas, Fatme ^a   Yost, Susan E ^a   Crane, Dennis T ^a   Lemercinier, Xavier ^a   Corbel, Michael J ^a  

^a NATIONAL INSTITUTE FOR BIOLOGICAL STANDARDS AND CONTROL   (United Kingdom)

Author keywords

Hib; Stability; Structure

Indexed keywords

HAEMOPHILUS INFLUENZAE VACCINE; OLIGOSACCHARIDE;

ARTICLE; CHEMICAL ANALYSIS; CONJUGATE; DRUG STABILITY; FREEZING; HAEMOPHILUS INFLUENZAE TYPE B; IMMUNOGENICITY; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN CONFORMATION; RABBIT; STORAGE; THAWING;

ANIMALS; ANTIBODIES, BACTERIAL; BACTERIAL PROTEINS; BLOOD BACTERICIDAL ACTIVITY; CHEMISTRY, PHYSICAL; CIRCULAR DICHROISM; DRUG STORAGE; FEMALE; HAEMOPHILUS VACCINES; IMMUNOGLOBULIN G; MICE; MICE, INBRED CBA; MOLECULAR WEIGHT; OLIGOSACCHARIDES; POLYSACCHARIDES; POLYSACCHARIDES, BACTERIAL; PROTEIN CONFORMATION; RABBITS; SPECTROMETRY, FLUORESCENCE; TEMPERATURE; VACCINES, CONJUGATE;

EID: 0035971978     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(01)00024-X     Document Type: Article

References (38)

1. Decline of childhood Haemophilus influenzae type b (Hib) disease in the Hib vaccine era
2. Experience in Finland with Haemophilus influenzae type b (Hib) disease in the Hib vaccine era
3. Declining incidence of Haemophilus influenzae type b disease since introduction of vaccination
4. Further studies on the immunogenicity of Haemophilus influenzae type b and pneumococcal type 6A polysaccharide-protein conjugates
5. Interaction of Haemophilus influenzae type b conjugate vaccines with diphtheria-tetanus-pertussis vaccine in control tests
6. Haemophilus type b conjugate vaccine
7. Recommendations for the production and control of Haemophilus influenzae type b conjugate vaccine
8. Physicochemical studies of the structure and stability of polysaccharide-protein conjugate vaccines
9. Analytical procedures used in the control of bacterial glycoconjugate vaccines
10. WHO/NIBSC-Co-sponsored informal workshop on the use of physicochemical methods for the characterization of Haemophilus influenzae type b conjugate vaccines
11. The development and current status of glycoconjugate vaccines
12. Molecular size characterization of Haemophilus influenzae type b polysaccharide-protein conjugate vaccines
13. A routine high-performance size-exclusion chromatography to determine molecular size distribution of Haemophilus influenzae type b conjugate vaccines
14. The amino-acid sequence of two non-toxic mutants of diphtheria toxin: CRM45 and CRM197
15. Effect of pH on the conformation of diphtheria toxin and its implications for membrane penetration
16. Variable selection method improves the prediction of protein secondary structure from circular dichroism spectra
17. Structural information on proteins from circular dichroism spectroscopy: Possibilities and limitations
18. Estimation of globular protein secondary structure from circular dichroism
19. Contin: A general purpose constrained regularization program for inverting noisy linear algebraic and integral equations
20. Calculation of protein conformation from circular dichroism
21. Measurement of anti-Haemophilus influenzae type b capsular polysaccharide antibodies by ELISA
22. ELISA methodology for polysaccharide antigens: Protein coupling of polysaccharides for adsorption to plastic tubes
23. Comparison of the diphtheria mutant toxin, CRM197, with a Haemophilus influenzae type-b polysaccharide-CRM197 conjugate by optical spectroscopy
24. Classical light scattering for the determination of absolute molecular weights and gross conformation of biological macromolecules
25. Aromatic contributions to circular dichroism spectra of proteins
26. 13C-n.m.r.-spectral and chemical characterization of the end- group and repeating-unit components of oligosaccharides derived by acid hydrolysis of Haemophilus influenzae type b capsular polysaccharide
27. Structural studies and chemistry of bacterial capsular polysaccharides. Investigations of phosphodiester-linked capsular polysaccharides isolated from Hemophilus influenzae types a,b,c and f: N M R spectroscopic idenfication and chemical modification of end groups and the nature of base-catalysed hydrolytic depolymerisation
28. Safety and immunogenicity of Haemophilus influenzae type b oligosaccharide-CRM197 conjugate vaccine in infants aged 15 to 23 months
29. Comparative trial in infants of four conjugate Haemophilus influenzae type b vaccines
30. Avidity and bactericidal activity of antibody elicited by different Haemophilus influenzae type b conjugate vaccines. The vaccine study group
31. Adjuvant properties of aluminium and calcium compounds
32. Lot-release criteria, postlicensure quality control, and the Haemophilus influenzae type b conjugate vaccines
33. Differences in the immunogenicity of three Haemophilus influenzae type b conjugate vaccines in infants
34. Role of contact and soluble factors in the growth and differentiation of B cells by helper T cells
35. T-cell antigenic sites tend to be amphipathic structures
36. 197 conjugate vaccines