Plasmid DNA encoding caprine interferon gamma inhibits antibody response to caprine arthritis-encephalitis virus (CAEV) surface protein encoded by a co-administered plasmid expressing CAEV env and tat genes

Vaccine

Volumn 19, Issue 23-24, 2001, Pages 3209-3215

  Cheevers, William P ^a   Beyer, Joseph C ^a   Hötzel, Isidro ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Antibody response; CAEV env and tat genes; Caprine arthritis encephalitis virus (CAEV); Caprine interferon gamma; Plasmid DNA

Indexed keywords

COAT PROTEIN; GAMMA INTERFERON; PLASMID DNA; PLASMID VECTOR; VIRUS ENVELOPE PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; CAPRINE ARTHRITIS ENCEPHALITIS VIRUS; CONTROLLED STUDY; GENE EXPRESSION; GOAT; IMMUNE RESPONSE; IMMUNIZATION; LYMPH NODE; NONHUMAN; PRIORITY JOURNAL; VIRUS EXPRESSION;

ANIMALS; ANTIBODIES, VIRAL; ARTHRITIS-ENCEPHALITIS VIRUS, CAPRINE; B-LYMPHOCYTES; GENE EXPRESSION; GENES, ENV; GENES, TAT; GOAT DISEASES; GOATS; INTERFERON TYPE II; LENTIVIRUS INFECTIONS; LYMPHOCYTE ACTIVATION; PLASMIDS; VACCINES, DNA; VIRAL ENVELOPE PROTEINS; VIRAL VACCINES;

EID: 0035971968     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(01)00006-8     Document Type: Article

References (32)

1. The lentiviruses of sheep and goats
2. Retroviruses and their roles in chronic inflammatory diseases and autoimmunity
3. Type 1 and type 2 cytokine gene expression by viral gp135 surface protein-activated T lymphocytes in caprine arthritis-encephalitis lentivirus infection
4. Functional diversity of helper T lymphocytes
5. Development of Th1 and Th2 populations and the nature of immune responses to hepatitis B virus DNA vaccines can be modulated by codelivery of various cytokine genes
6. In vivo modulation of vaccine-induced immune responses toward a Th1 phenotype increases potency and vaccine effectiveness in a herpes simplex virus type 2 mouse model
7. In vivo engineering of a cellular immune response by coadministration of IL-12 expression vector with a DNA immunogen
8. Enhancement of cell-mediated immunity against HIV-1 induced by coinoculation of plasmid-encoded HIV-1 antigen with plasmid expressing IL-12
9. IL-12 delivery from recombinant vaccinia virus attenuates the vector and enhances the cellular immune response against HIV-1 env in a dose-dependent manner
10. Cytokine in adjuvant steering of the immune response phenotype to HIV-1 vaccine constructs, granulocyte-macrophage colony stimulating factor and TNF-α synergize with IL-12 to enhance induction of cytotoxic T lymphocytes
11. Interleukin-18 modulates immune responses induced by HIV-1 Nef DNA prime/protein boost vaccine
12. Immunization with plasmid DNA expressing the caprine arthritis-encephalitis virus envelope gene: Quantitative and qualitative aspects of antibody response to viral surface glycoprotein
13. Cloning and expression of caprine interferon-gamma
14. Genetic structure of the pol-env region of the caprine arthritis-encephalitis lentivirus genome
15. Targeting of the visna virus tat protein to AP-1 sites: Interactions with bZIP domains of Fos and Jun in vitro and in vivo
16. Immune response to caprine arthritis-encephalitis virus surface protein induced by coimmunization with recombinant vaccinia virus expressing the caprine arthritis-encephalitis virus envelope gene and caprine interleukin-12
17. Depressed CD4+ T lymphocyte proliferative response and enhanced antibody response to viral antigen in chronic lentivirus-induced arthritis
18. Monoclonal antibodies to conformational epitopes of the surface glycoprotein of caprine arthritis-encephalitis virus: Potential application to competitive inhibition enzyme linked immunosobent assay for detecting antibodies in goat sera
19. Modulation of antigen-specific humoral responses in Rhesus macaques using cytokine cDNAs as DNA vaccine adjuvants
20. HIV-1 DNA vaccines and chemokines
21. Antigen specific humoral and cellular immune responses can be modulated in rhesus macques through the use of IFN-γ, IL-12, or IL-18 gene adjuvants
22. Factors influencing cellular immune responses to feline immunodeficiency virus induced by DNA vaccination
23. Protection against FIV challenge infection by genetic vaccination using minimalistic DNA constructs for FIV env gene and feline IL-12 expression
24. Th1 and Th2 subsets: Paradigms lost?
25. Bovine type 1 and type 2 responses
26. How the MHC selects Th1/Th2 immunity
27. Interferon-gamma inhibits transgene expression driven by SV40 and CMV promoters but augments expression driven by the mammalian MHC I promoter
28. Activation of caprine arthritis-encephalitis virus long terminal repeat by gamma interferon
29. Pronounced acute immunosuppression in vivo mediated by HIV tat challenge
30. HIV-1 tat protein differentially modulates the B cell response of naïve, memory, and germinal center B cells
31. Human immunodeficiency virus 1 tat binds to dipeptidyl aminopepsidase IV (CD26): A possible mechanism of tat's immunosuppressive activity
32. Interferon α and Tat involvement in the immunosuppression of uninfected T cells and C-C chemokine decline in AIDS