Interpretability and robustness of sieve analysis models for assessing HIV strain variations in vaccine efficacy

Statistics in Medicine

Volumn 20, Issue 2, 2001, Pages 263-279

  Gilbert, Peter B ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS VACCINE;

ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DATA ANALYSIS; DRUG EFFICACY; DRUG SENSITIVITY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NONHUMAN; PHASE 3 CLINICAL TRIAL; STATISTICAL ANALYSIS; STRAIN DIFFERENCE; VIRUS STRAIN;

AIDS VACCINES; CLINICAL TRIALS, PHASE III; COMPUTER SIMULATION; DATA INTERPRETATION, STATISTICAL; HIV INFECTIONS; HIV-1; HUMANS; LOGISTIC MODELS; MODELS, IMMUNOLOGICAL; SENSITIVITY AND SPECIFICITY; THAILAND; VACCINATION;

EID: 0035970126     PISSN: 02776715     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0258(20010130)20:2<263::AID-SIM660>3.0.CO;2-1     Document Type: Article

References (25)

1. Genetic and immunologic characterization of viruses infecting MN-rgp 120 vaccinated volunteers
2. Statistical methods for assessing differential vaccine protection against HIV types
3. Separate sample logistic discrimination
4. Regression and ordered categorical variables
5. Regression models for ordinal data
6. Maximum likelihood estimation in semiparametric selection bias models with application to AIDS vaccine trials
7. Interpretation and estimation of vaccine efficacy under heterogeneity
8. Emerging recombinant human immunodeficiency viruses: Uneven representation of the envelope V3 region
9. Assessment of the protective efficacy of vaccines against common diseases using case-control and cohort studies
10. Applying Cox regression to competing risks
11. The analysis of failure times in the presence of competing risks
12. A frailty mixture model for estimating vaccine efficacy
13. Exposure and change in contact rates in evaluating prophylactic HIV vaccines in the field
14. Comparison of competing risks failure time methods and time-independent methods for assessing strain variations in vaccine protection
15. Feasibility of an HIV-1 vaccine efficacy trial among injecting drug users (IDUs) in Bangkok, Thailand
16. Estimability and interpretation of vaccine efficacy using frailty mixing models
17. Estimation of vaccine efficacy in the presence of waning: Application to cholera vaccines
18. Comparing two smoothing methods for exploring waning vaccine effects
19. Topics in likelihood-based methods for longitudinal data analysis
20. A random-effect ordinal regression model for multi-level analysis
21. Random effects in ordinal regression models
22. Distribution-free fitting of logit models with random effects for repeated categorical responses