Salivary Acinar Cells from Aquaporin 5-deficient Mice Have Decreased Membrane Water Permeability and Altered Cell Volume Regulation

Journal of Biological Chemistry

Volumn 276, Issue 26, 2001, Pages 23413-23420

  Krane, Carissa M ^a   Melvin, James E ^b   Nguyen, Ha Van ^b   Richardson, Linda ^b   Towne, Jennifer E ^a   Doetschman, Thomas ^a   Menon, Anil G ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; COMPOSITION; ELECTROLYTES; MECHANICAL PERMEABILITY; OSMOSIS;

HOMEOSTASIS; SALIVA;

CELL MEMBRANES;

AQUAPORIN; AQUAPORIN 5; ELECTROLYTE; UNCLASSIFIED DRUG; WATER; AQP5 PROTEIN, MOUSE; MEMBRANE PROTEIN; MERCURY; MESSENGER RNA;

ACINAR CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL VOLUME; ELECTROLYTE TRANSPORT; EMBRYO; EMBRYO CELL; FEMALE; FLOW RATE; MALE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; SALIVARY GLAND; SALIVATION; STEM CELL; SUBLINGUAL GLAND; WATER TRANSPORT; ANIMAL; BIOSYNTHESIS; BLOOD GAS ANALYSIS; BODY WATER; CELL CULTURE; CELL SIZE; CHEMISTRY; CYTOLOGY; DRINKING; DRUG EFFECT; ELECTROLYTE BALANCE; GENETICS; METABOLISM; MOUSE; MOUSE MUTANT; OSMOLARITY; OSMOTIC PRESSURE; PHYSIOLOGY; SALIVA; SECRETION; URINE; WESTERN BLOTTING;

ANIMALIA;

ANIMALS; AQUAPORIN 5; AQUAPORINS; BLOOD GAS ANALYSIS; BLOTTING, WESTERN; BODY WATER; CELL MEMBRANE PERMEABILITY; CELL SIZE; CELLS, CULTURED; DRINKING; MEMBRANE PROTEINS; MERCURY; MICE; MICE, KNOCKOUT; OSMOLAR CONCENTRATION; OSMOTIC PRESSURE; RNA, MESSENGER; SALIVA; SALIVARY GLANDS; URINE; WATER-ELECTROLYTE BALANCE;

EID: 0035968332     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M008760200     Document Type: Article

References (30)

1. Bivona, P. L. (1998) N. Y. State Dent. J. 64, 46-52
2. Astor, F. C., Hanft, K. L., and Ciocon, J. O. (1999) Ear Nose Throat J. 78, 476-479
3. Fox, P. C. (1998) Ann. N. Y. Acad. Sci. 842, 132-137
4. Turner, R. J., Paulais, M., Manganel, M., Lee, S. I., Moran, A. and Melvin, J. E. (1993) Crit. Rev. Oral Biol. Med. 4, 384-391
5. He, X., Tse, C.-M., Donowitz, M., Alper, S. L., Gabriel, S. E., and Baum, B. J. (1997) Pfluegers Arch. 433, 260-268
6. Foskett, J. K., and Melvin, J. E. (1989) Science 244, 1582-1585
7. Foskett, J. K. (1990) Am. J. Physiol. 259, C998-C1004
8. Steward, M. C., Seo, Y., Murakami, M., Seo, J. T., Larcombe-McDouall, J. B., and Case, R. M. (1998) Eur. J. Morphol. 36, 103-106
9. Matsuzaki, T., Suzuki, T., Koyama, H., Tanaka, S., and Takata, K. (1999) Cell Tissue Res. 295, 513-521
10. Ma, T., Song, Y., Gillespie, A., Carlson, E. J., Epstein, C. J., and Verkman, A. S. (1999) J. Biol. Chem. 274, 20071-20074
11. Fischer, D., and Ship, J. A. (1997) Special Care Dent. 17, 58-64
12. Silanikove, N., and Tadmor, A. (1989) Am. J. Physiol. 256, R809-815
13. Krane, C. M., Towne, J. E., and Menon, A. G. (1999) Mamm. Genome 10, 498-505
14. Schultheis, P. J., Clarke, L. L., Meneton, P., Harline, M., Boivin, G. P., Stemmermann, G., Duffy, J. J., Doetschman, T., Miller, M. L., and Shull, G. E. (1998) J. Clin. Invest. 101, 1243-1253
15. Askew, G. R., Doetschman, T., and Lingrel, J. B. (1993) Mol. Cell. Biol. 13, 4115-4124
16. Stewart, C. L. (1993) Methods Enzymol. 225, 823-856
17. Evans, R. L., Bell, S. M., Schultheis, P. J., Shull, G. E., and Melvin, J. E. (1999) J. Biol. Chem. 274, 29025-29030
18. Schreiber, R., Nitschke, R., Greger, R., and Kunzelmann, K. (1999) J. Biol. Chem. 270, 1908-1912
19. Spicer, A., Miller, M. L., Andringa, A., Riddle, T. M., Duffy, J. J., Doetschman, T., and Shull, G. E. (2000) J. Biol. Chem. 275, 21555-21565
20. Heymann, J. B., and Engel, A. (2000) J. Mol. Biol. 295, 1039-1053
21. Jung, J. S., Preston, G. M., Smith, B. L., Guggino, W. B., and Agre, P. (1994) J. Biol. Chem. 269, 14648-14654
22. Raina, S., Preston, G. M., Guggino, W. B., and Agre, P. (1995) J. Biol. Chem. 270, 1908-1912
23. King, L. S., Yasui, M., and Agre, P. (2000) Mol. Med. Today 6, 60-65
24. Lee, M. D., King, L. S., and Agre, P. (1997) Medicine (Baltimore) 76, 141-156
25. Ma, T., Yang, B., Gillespie, A., Carlson, E. J., Epstein, C. J., and Verkman, A. S. (1998) J. Biol. Chem. 273, 4296-4299
26. Ma, T., Song, Y., Yang, B., Gillespie, A., Carlson, E. J., Epstein, C. J., and Verkman, A. S. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 4386-4391
27. Ma, T., Yang, B., Gillespie, A., Carlson, E. J., Epstein, C. J., and Verkman, A. S. (1997) J. Clin. Invest. 100, 957-962
28. Cook, D. I., Van Lennep, E. W., Roberts, M. L., and Young, J. A. (1994) in Physiology of the Gastrointestinal Tract (Johnson, L. R., ed) 3rd Ed., pp. 1061-1117, Raven Press, New York
29. Evans, R. L., Park, K., Turner, R. J., Watson, G. E., Nguyen, H. V., Dennett, M. R., Hand, A. R., Flagella, M., Shull, G. E., and Melvin, J. E. (2000) J. Biol. Chem. 275, 26720-26726
30. Yasui, M., Hazama, A., Kwon, T. H., Nielsen, S., Guggino, W. B., and Agre, P. (1999) Nature 402, 184-187