An in vitro investigation of the suitability of press-coated tablets with hydroxypropylmethylcellulose acetate succinate (HPMCAS) and hydrophobic additives in the outer shell for colon targeting

Journal of Controlled Release

Volumn 70, Issue 1-2, 2001, Pages 97-107

  Fukui, Eiji ^a   Miyamura, Nobuteru ^a   Kobayashi, Masao ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

Calcium stearate; Colon targeting formulation; Hydroxypropylmethylcellulose acetate succinate; Magnesium stearate; Press coated tablet

Indexed keywords

AQOAT; BARIUM DERIVATIVE; CALCIUM DERIVATIVE; CARBOXYMETHYLCELLULOSE; CITRATE CALCIUM; DILTIAZEM; DRUG ADDITIVE; HYDROGENATED CASTOR OIL; HYDROXYPROPYLMETHYLCELLULOSE ACETATE SUCCINATE; K3WAX; MAGNESIUM STEARATE; MYRISTIC ACID; PALMITIC ACID; POTASSIUM DERIVATIVE; POVIDONE; STARCH; STEARIC ACID;

ARTICLE; COLON; DRUG FORMULATION; DRUG SOLUBILITY; DRUG TARGETING; ENTERIC COATED TABLET; HYDROPHOBICITY; IN VITRO STUDY; PH; PRIORITY JOURNAL; SMALL INTESTINE; STOICHIOMETRY; TABLET COMPRESSION; TIMED DRUG RELEASE;

COLON; DILTIAZEM; HYDROGEN-ION CONCENTRATION; METHYLCELLULOSE; PRESSURE; SOLUBILITY; TABLETS;

EID: 0035966535     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(00)00332-1     Document Type: Article

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