Partial Phosphorylation of the N-Formyl Peptide Receptor Inhibits G Protein Association Independent of Arrestin Binding

Journal of Biological Chemistry

Volumn 276, Issue 52, 2001, Pages 49195-49203

  Bennett, Teresa A ^a,b   Foutz, Terry D ^b   Gurevich, Vsevolod V ^c   Sklar, Larry A ^b,d   Prossnitz, Eric R ^a  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NEW MEXICO   (United States)

^c SUN HEALTH RESEARCH INSTITUTE   (United States)

^d National Flow Cytometry Resource   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYME INHIBITION;

PHOSPHORYLATION;

PROTEINS;

ARRESTIN 2; FORMYLPEPTIDE; FORMYLPEPTIDE RECEPTOR; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; RETINA S ANTIGEN; UNCLASSIFIED DRUG; CHEMOTACTIC PEPTIDE RECEPTOR; GTP BINDING PROTEINS; IMMUNOGLOBULIN RECEPTOR; RECEPTOR;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; FLUOROMETRY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RECEPTOR DOWN REGULATION; WILD TYPE; AMINO ACID SEQUENCE; ANIMAL; BIOLOGICAL MODEL; CELL LINE; CELL MEMBRANE; CHEMISTRY; FLUORESCENCE MICROSCOPY; GENETICS; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SPECTROFLUOROMETRY;

AMINO ACID SEQUENCE; ANIMAL; ARRESTIN; CELL LINE; CELL MEMBRANE; GTP-BINDING PROTEINS; HUMAN; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, IMMUNOLOGIC; RECEPTORS, PEPTIDE; SPECTROMETRY, FLUORESCENCE; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0035966001     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M106414200     Document Type: Article

References (42)

1. Koenig, J. A., and Edwardson, J. M. (1997) Trends Pharmacol. Sci. 18, 276-287
2. Lefkowitz, R. J. (1998) J. Biol. Chem. 273, 18677-18680
3. Zhang, J., Ferguson, S. S., Barak, L. S., Aber, M. J., Giros, B., Lefkowitz, R. J., and Caron, M. G. (1997) Receptors and Channels 5, 193-199
4. Gurevich, V. V., Dion, S. B., Onorato, J. J., Ptasienski, J., Kim, C. M., Sterne-Marr, R., Hosey, M. M., and Benovic, J. L. (1995) J. Biol. Chem. 270, 720-731
5. Lohse, M. J., Andexinger, S., Pitcher, J., Trukawinski, S., Codina, J., Faure, J. P., Caron, M. G., and Lefkowitz, R. J. (1992) J. Biol. Chem. 267, 8558-8564
6. Goodman, O. B., Jr., Krupnick, J. G., Santini, F., Gurevich, V. V., Penn, R. B., Gagnon, A. W., Keen, J. H., and Benovic, J. L. (1996) Nature 383, 447-450
7. Gilbert, T. L., Bennett, T. A., Maestas, D. C., Cimino, D. F., and Prossnitz, E. R. (2001) Biochemistry 40, 3467-3475
8. Roseberry, A. G., and Hosey, M. M. (2001) J. Cell Sci. 114, 739-746
9. Miller, W. E., and Lefkowitz, R. J. (2001) Curr. Opin. Cell Biol. 13, 139-145
10. Prossnitz, E. R., and Ye, R. D. (1997) Pharmacol. Ther. 74, 73-102
11. Davies, E. V., and Hallett, M. B. (1998) Int. J. Mol. Med. 1, 485-490
12. Jordan, J. E., Zhao, Z. Q., and Vinten-Johansen, J. (1999) Cardiovasc. Res. 43, 860-878
13. Ricevuti, G. (1997) Ann. N. Y. Acad. Sci. 832, 426-448
14. Maestes, D. C., Potter, R. M., and Prossnitz, E. R. (1999) J. Biol. Chem. 274, 29791-29795
15. Wilden, U., Hall, S. W., and Kuhn, H. (1986) Proc. Natl. Acad. Sci. U. S. A. 83, 1174-1178
16. Gibson, S. K., Parkes, J. H., and Liebman, P. A. (2000) Biochemistry 39, 5738-5749
17. Pitcher, J. A., Freedman, N. J., and Lefkowitz, R. J. (1998) Annu. Rev. Biochem. 67, 653-692
18. Bennett, T. A., Maestas, D. C., and Prossnitz, E. R. (2000) J. Biol. Chem. 275, 24590-24594
19. Prossnitz, E. R., Quehenberger, O., Cochrane, C. G., and Ye, R. D. (1993) Biochem. J. 294, 581-587
20. Gurevich, V. V., and Benovic, J. L. (2000) Methods Enzymol. 315, 422-437
21. Hsu, M. H., Chiang, S. C., Ye, R. D., and Prossnitz, E. R. (1997) J. Biol. Chem. 272, 29426-29429
22. Sklar, L. A., Finney, D. A., Oades, Z. G., Jesaitis, A. J., Painter, R. G., and Cochrane, C. G. (1984) J. Biol. Chem. 259, 5661-5669
23. Sklar, L. A., Vilven, J., Lynam, E., Neldon, D., Bennett, T. A., and Prossnitz, E. (2000) BioTechniques 28, 976-985
24. Bennett, T. A., Key, T. A., Gurevich, V. V., Neubig, R., Prossnitz, E. R., and Sklar, L. A. (2001) J. Biol. Chem. 276, 22453-22460
25. Fay, S. P., Posner, R. G., Swann, W. N., and Sklar, L. A. (1991) Biochemistry 30, 5066-5075
26. Posner, R. G., Fay, S. P., Domalewski, M. D., and Sklar, L. A. (1994) Mol. Pharmacol. 45, 65-73
27. Sklar, L. A., Mueller, H., Omann, G., and Oades, Z. (1989) J. Biol. Chem. 264, 8483-8486
28. Benovic, J. L., Kuhn, H., Weyand, I., Codina, J., Caron, M. G., and Lefkowitz, R. J. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 8879-8882
29. Gurevich, V. V., Pals-Rylaarsdam, R., Benovic, J. L., Hosey, M. M., and Onorato, J. J. (1997) J. Biol. Chem. 272, 28849-28852
30. Bourne, H. R. (1997) Curr. Opin. Cell Biol. 9, 134-142
31. Conklin, B. R., and Bourne, H. R. (1993) Cell 73, 631-641
32. Wall, M. A., Coleman, D. E., Lee, E., Iniguez-Lluhi, J. A., Posner, B. A., Gilman, A. G., and Sprang, S. R. (1995) Cell 83, 1047-1058
33. Hirsch, J. A., Schubert, C., Gurevich, V. V., and Sigler, P. B. (1999) Cell 97, 257-269
34. Christophe, T., Rabiet, M. J., Tardif, M., Milcent, M. D., and Boulay, F. (2000) J. Biol. Chem. 275, 1656-1664
35. Kovoor, A., Celver, J., Abdryashitov, R. I., Chavkin, C., and Gurevich, V. V. (1999) J. Biol. Chem. 274, 6831-6834
36. Pals-Rylaarsdam, R., and Hosey, M. M. (1997) J. Biol. Chem. 272, 14152-14158
37. Pals-Rylaarsdam, R., Xu, Y., Witt-Enderby, P., Benovic, J. L., and Hosey, M. M. (1995) J. Biol. Chem. 270, 29004-29011
38. Zhang, J., Barak, L. S., Anborgh, P. H., Laporte, S. A., Caron, M. G., and Ferguson, S. S. (1999) J. Biol. Chem. 274, 10999-11006
39. Oakley, R. H., Laporte, S. A., Holt, J. A., Barak, L. S., and Caron, M. G. (1999) J. Biol. Chem. 274, 32248-32257
40. Zigmond, S. H., Sullivan, S. J., and Lauffenburger, D. A. (1982) J. Cell Biol. 92, 34-43
41. Gibson, S. K., Parkes, J. H., and Liebman, P. A. (1998) Biochemistry 37, 11393-11398
42. Key, T. A., Bennett, T. A., Gurevich, V. V., Sklar, L. A., and Prossnitz, E. R. (2001) J. Biol. Chem. 276, 49204-49212