Inhibition of human immunodeficiency virus type 1 reverse transcriptase, protease and integrase by bovine milk proteins

Life Sciences

Volumn 69, Issue 19, 2001, Pages 2217-2223

  Ng, T B ^a,b   Lam, T L ^a   Au, T K ^a   Ye, X Y ^a   Wan, C C ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

Author keywords

HIV 1; Integrase; Milk proteins; Protease; Reverse transcriptase

Indexed keywords

ALPHA LACTALBUMIN; ANGIOGENIN 1; BETA LACTOGLOBULIN; CASEIN; GLYCOLACTIN; GLYCOLIC ACID; INTEGRASE; LACTOFERRIN; LACTOGENIN; LACTOGLOBULIN; LACTOPEROXIDASE; MILK PROTEIN; PROTEINASE; RNA DIRECTED DNA POLYMERASE; UNCLASSIFIED DRUG;

ARTICLE; BIOASSAY; CATTLE; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LIFE CYCLE; NONHUMAN; PROTEIN ISOLATION; VIRUS INHIBITION;

ANIMALS; CATTLE; FEMALE; HIV INFECTIONS; HIV INTEGRASE; HIV PROTEASE; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; HUMANS; MILK PROTEINS; VIRUS REPLICATION;

EID: 0035964785     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(01)01311-X     Document Type: Article

References (16)

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2. Antiviral effect of bovine lactoferrin saturated with metal ions on early steps of human immunodeficiency virus type 1 infection
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4. First deomonstration of an inhibitory activity of milk proteins against human immunodeficiency virus-1 reverse transcriptase and the effect of succinylation
5. Isolation of lactoperoxidase and lactoferrins from bovine milk acid whey by carboxy-methyl cation exchange chromatography
6. Isolation and characterization of angiogenin-1 and a novel protein designated lactogenin from bovine milk
7. Purification and characterization of glycolactin, a novel glycoprotein from bovine milk
8. Inhibition of influenza virus fusion by polyanionic proteins
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10. A comparison of human immunodeficiency virus type-1 protease inhibition activities by the aqueous and methanol extracts of Chinese medicinal herbs
11. The plant ribosome inactivating proteins luffin and saporin are potent inhibitors of HIV integrase
12. Structural and functional analysis of negatively charged milk proteins with anti-HIV activity
13. Blocking of CD4 cell receptors for the human immunodeficiency virus type 1 (HIV-1) by chemically modified bovine milk proteins: Potential for AIDS prophylaxis
14. Bovine beta-lactoglobulin modified by 3-hydroxy-phthalic anhydride blocks the CD4 cell receptor for HIV
15. Effect of 3-hydroxyphthaloy-beta-lactoglobulin on vaginal transmission of simian immunodeficiency virus in rhesus monkeys
16. Anti-human immunodeficiency virus (anti-HIV) natural products with special emphasis on HIV reverse transcriptase inhibitors