The stability of benzoyl peroxide formulations determined from isothermal microcalorimetric studies

International Journal of Pharmaceutics

Volumn 225, Issue 1-2, 2001, Pages 135-143

  Zaman, Flora ^a   Beezer, Anthony E ^a,c   Mitchell, John C ^a   Clarkson, Quentin ^b   Elliot, J ^b   Nisbet, M ^b   Davis, Adrian F ^b  

^a UNIVERSITY OF GREENWICH   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Benzoyl peroxide; Calorimetry; Formulation excipients; Stability

Indexed keywords

BENZOYL PEROXIDE; CARBOMER; DIAZOLIDINYL UREA; EXCIPIENT; MONAWET; POLOXAMER; POLYTRAP; SIPERNAT; UNCLASSIFIED DRUG; XANTHAN;

AQUEOUS SOLUTION; ARTICLE; DATA ANALYSIS; DRUG DESIGN; DRUG FORMULATION; DRUG STABILITY; KINETICS; MICROCALORIMETRY; PRIORITY JOURNAL; TEMPERATURE; THERMODYNAMICS;

BENZOYL PEROXIDE; CALORIMETRY; CHEMISTRY, PHARMACEUTICAL; DRUG STABILITY; KINETICS;

EID: 0035964469     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(01)00772-4     Document Type: Article

References (8)

1. Direct determination of equilibrium thermodynamic and kinetic parameters from isothermal heat conduction microcalorimetry
2. Benzoyl peroxide stability in pharmaceutical gel preparations
3. Benzoyl peroxide solubility and stability in hydric solvents
4. Temperature induced aggregation in aqueous solution of a series of PEO-PPO-PEO copolymers
5. Influence of solvents on paraben permeation through idealized skin model membranes
6. Determination of thermodynamic and kinetic parameters from isothermal heat conduction microcalorimetry: Applications to long term reaction studies
7. The stability of benzoyl peroxide by isothermal microcalorimetry