Effects of phospholipase A2 activating peptides upon GTP-binding protein-evoked adrenocorticotrophin secretion

European Journal of Pharmacology

Volumn 424, Issue 3, 2001, Pages 163-171

  Guild, Simon B ^a  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

Author keywords

ACTH (adrenocorticotrophin); Anterior pituitary; Exocytosis; G protein; Phospholipase A2

Indexed keywords

2 (4 AMYLCINNAMIDO) 4 CHLOROBENZOIC ACID; ARACHIDONIC ACID; ARACHIDONYL TRIFLUOROMETHYL KETONE; CALCIUM ION; CORTICOTROPIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); IBUPROFEN; MASTOPARAN; MELITTIN; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR;

ADENOHYPOPHYSIS; ANIMAL CELL; ARACHIDONIC ACID METABOLISM; ARTICLE; CELL MEMBRANE PERMEABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORTICOTROPIN RELEASE; ENZYME ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM;

ADRENOCORTICOTROPIC HORMONE; ANIMALS; ARACHIDONIC ACID; ARACHIDONIC ACIDS; CALCIUM; CELL MEMBRANE PERMEABILITY; CYCLOOXYGENASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; GTP-BINDING PROTEINS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); IBUPROFEN; MELITTEN; PEPTIDES; PHOSPHOLIPASES A; PROTEINS; TUMOR CELLS, CULTURED; WASP VENOMS;

EID: 0035958748     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(01)01149-9     Document Type: Article

References (42)

1. Role of arachidonic acid in the regulation of adrenocorticotrophin release from rat anterior pituitary cell cultures
2. 2 activity by mastoparan, a new class of mast cell degranulating peptides from wasp venom
3. Stress hormones: Their interaction and regulation
4. 2 and phospholipase-C in human-platelets exposed to epinephrine-role of glycoprotein-iib glycoproteins-iiia and dual role of epinephrine
5. Selective-inhibition of receptor-coupled phospholipase-C-dependent processes in human platelets and polymorphonuclear neutrophils
6. Stimulus-secretion coupling: The concept and clues from chromaffin and other cells
7. Heterotrimeric G-protein candidates for Ge in the ACTH secretory pathway
8. Protein and cell membrane iodinations with a sparingly soluble chloramide, 1, 3, 4, 6-tetrachloro-3α, 6α-diphenyl-glycoluril
9. Trimeric G-proteins control exocytosis in chromaffin cells-Go regulates the peripheral actin network and catecholamine secretion by a mechanism involving the small GTP-binding protein Rho
10. GE: GTP-binding protein mediating exocytosis
11. Effects of adenosine 3′:5′-cyclic monophosphate and guanine nucleotides on calcium-evoked ACTH release from electrically-permeabilised AtT-20 cells
12. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
13. Somatostatin inhibits multireceptor stimulation of cAMP-formation and corticotroph secretion in mouse pituitary tumour cells
14. Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins)
15. Regulation of Gi and Go by mastoparan, related amphiphilic peptides, and hydrophobic amines; Mechanisms and structural determinants of activity
16. 2 inhibition by alkylbenzoylacrylic acids
17. Calcium-dependence of catecholamine release from adrenal medulary cells after exposure to intense electric fields
18. Gaining access to the cytosol: The technique and some applications of electropermeabilization
19. 2 and insulin secretion in pancreatic islets
20. Direct control of exocytosis by receptor-mediated activation of the heterotrimeric GTPases Gi and Go or by the expression of their active Gα subunits
21. Inhibitors of the cytochrome P-450 enzymes block the secretagogue-induced release of corticotrophin in mouse pituitary tumour cells
22. Dual regulation of ACTH secretion by guanine nucleotides in permeabilised AtT-20 cells
23. Evidence that a receptor-linked G-protein inhibits exocytosis by a post-second messenger mechanism in AtT-20 cells
24. Effects of protein kinase C activators upon the late stages of the ACTH secretory pathway of AtT-20 cells
25. The effects of mastoparan upon the late stages of the ACTH secretory pathway of AtT-20 cells
26. The effects of calyculin A upon calcium and guanine nucleotide stimulated ACTH secretion from permeabilised AtT-20 pituitary tumour cells
27. The roles of adenosine 3′, 5′-cyclic monophosphate-dependent kinase A and protein kinase C in stimulus-secretion coupling in AtT-20 cells
28. Involvement of multiple protein kinase C isozymes in the ACTH secretory pathway of AtT-20 cells
29. 2-activating peptide and G-proteins β-subunits
30. Functional dissociation between glucocorticoid-induced decrease in arachidonic acid release and inhibition of adrenocorticotrophic hormone secretion in AtT-20 corticotrophs
31. Somatostatin desensitisation; loss of the ability of somatostatin to inhibit cAMP accumulation and ACTH release
32. Storage and secretion of β-endorphin and related peptides by mouse pituitary tumour cells: Regulation by glucocorticoids
33. 2
34. Exocytosis in chromaffin cells: Possible involvement of the heterotrimeric GTP-binding protein Go
35. Exocytosis in chromaffin cells: Evidence for a Mg ATP-independent step that requires a pertussis-toxin-sensitive GTP-binding protein
36. Trimeric G-proteins in vesicular trafficking-possible involvement of the secretory granule-bound Go in regulated exocytosis
37. Trimeric G-proteins control regulated exocytosis in bovine chromaffin cells-sequential involvement of Go-associated with secretory granules and Gi3 bound to the plasma membrane
38. Exocytosis in single chromaffin cells: Regulation by secretory granule-associated Go protein
39. Beta-endorphin and adrenocorticotrophin release from rat adenohypophysis in vitro: Evidence for local modulation by arachidonic acid metabolites of the cyclo-oxygenase and lipoxygenase pathway
40. 2 formed locally in response to vasopressin and corticotrophin-releasing factor
41. Mastoparan interacts with the carboxy terminus of the α subunit of Gi
42. Role of lipoxygenase metabolites of arachidonic acid in the regulation of ACTH secretion by perifused rat anterior pituitary cells