Sleep inducing effects of propofol microinjection into the medial preoptic area are blocked by flumazenil

Brain Research

Volumn 908, Issue 2, 2001, Pages 155-160

  Tung, Avery ^a   Bluhm, Bryan ^a   Mendelson, Wallace B ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

Benzodiazepine receptor; Flumazenil; Propofol; Sleep

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ALCOHOL; BENZODIAZEPINE RECEPTOR; BENZODIAZEPINE RECEPTOR BLOCKING AGENT; FLUMAZENIL; INTRALIPID; PENTOBARBITAL; PROPOFOL; TRIAZOLAM;

ANIMAL EXPERIMENT; CONFERENCE PAPER; CONTROLLED STUDY; MALE; MEDIAL PREOPTIC AREA; MICROINJECTION; NONHUMAN; NONREM SLEEP; PRIORITY JOURNAL; RAT; REM SLEEP; SLEEP PATTERN; SLEEP STAGE; SLEEP TIME; WAKEFULNESS;

ANESTHETICS, INTRAVENOUS; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; FLUMAZENIL; GABA MODULATORS; MALE; NEURONS; PREOPTIC AREA; PROPOFOL; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; SLEEP; SLEEP, REM;

EID: 0035958524     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)02629-4     Document Type: Conference Paper

References (21)

1. Effect of p-chlorophenylalanine and tryptophan on sleep, EEG and motor activity in the rat
2. Cortical synchronization and sleep patterns in acute restrained and chronic behaving cats induced by basal forebrain stimulation
3. Lack of effect of flumazenil on the reversal of propofol anaesthesia
4. α4β2 neuronal nicotinic acetylcholine receptors in the central nervous system are inhibited by isoflurane and propofol, but α7-type nicotinic acetylcholine receptors are unaffected
5. The actions of propofol on inhibitory amino acid receptors of bovine adrenomedullary chromaffin cells and rodent central neurones
6. RO15-1788 decreases hypnotic effects of sleep deprivation
7. Liberation from mechanical ventilation: A decade of progress
8. Sleep suppression after basal forebrain lesions in the cat
9. Neuropharmacology of sleep induction by benzodiazepines
10. Sleep-inducing effects of adenosine microinjections into the medial preoptic area are blocked by flumazenil
11. Sleep induction by microinjection of pentobarbital into the medial preoptic area in rats
12. Characterization of the hypnotic effects of triazolam microinjections in to the medial preoptic area
13. Injection of solutions into cerebral tissue: Relation between volume and diffusion
14. AchE stained horizontal sections of the rat brain in stereotaxic coordinates
15. Nonbarbiturate intravenous anesthetics
16. Propofol and flurazepam act synergistically to potentiate GABAA receptor activation in human recombinant receptors
17. Propofol and midazolam act synergistically in combination
18. Propofol anesthesia increases dopamine and serotonin activities at the somatosensory cortex in rats: A microdialysis study
19. REM sleep induction by physostigmine infusion during sleep in normal volunteers
20. Effects of ethanol injection to the preoptic area on sleep and temperature in rats
21. Are anesthetics sleeping pills? Sleep induction by injection of propofol into the medial preoptic area of rats