Evidence of macrophage foam cell formation by very low-density lipoprotein receptor: Interferon-γ inhibition of very low-density lipoprotein receptor expression and foam cell formation in macrophages

Circulation

Volumn 103, Issue 8, 2001, Pages 1142-1147

  Kosaka, Shotaro ^a   Takahashi, Sadao ^a   Masamura, Katsuhiko ^a   Kanehara, Hideo ^a   Sakai, Juro ^b   Tohda, Gen ^a   Okada, Eiko ^a   Oida, Koji ^a   Iwasaki, Tadao ^c   Hattori, Hiroaki ^c   Kodama, Tatsuhiko ^d   Yamamoto, Tokuo ^e   Miyamori, Isamu ^a  

^a UNIVERSITY OF FUKUI   (Japan)

^b TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c BML   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e TOHOKU UNIVERSITY   (Japan)

Author keywords

Cells; Interferon ; Lipoproteins; Proteins; Receptors

Indexed keywords

GAMMA INTERFERON; VERY LOW DENSITY LIPOPROTEIN RECEPTOR;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CELL DIFFERENTIATION; CELL TRANSFORMATION; DRUG RECEPTOR BINDING; FOAM CELL; HUMAN; HUMAN CELL; MACROPHAGE ACTIVATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RECEPTOR BINDING; RECEPTOR UPREGULATION; T LYMPHOCYTE ACTIVATION;

EID: 0035957032     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.103.8.1142     Document Type: Article

References (43)

1. Rabbit very low density lipoprotein receptor: A low density lipoprotein receptor-like protein with distinct ligand specificity
2. Structure, chromosome location, and expression of the human very low density lipoprotein receptor gene
3. The human LDL receptor: A cystein-rich protein with multiple Alu sequences in its mRNA
4. Very low density lipoprotein receptor binds apolipoprotein E2/2 as well as apolipoprotein E3/3
5. Enhancement of the binding of triglyceride-rich lipoprotein to the very low density lipoprotein receptor by apolipoprotein E and lipoprotein lipase
6. The atherogenic lipoprotein Lp(a) is internalized and degraded in a process mediated by the VLDL receptor
7. Lipoprotein metabolism in the macrophage: Implications for cholesterol deposition in atherosclerosis
8. Expression of very low density lipoprotein receptor mRNA in rabbit atherosclerotic lesions
9. Expression of VLDL receptor in the vascular wall
10. Expression of LDL receptor, VLDL receptor, LDL receptor-related protein, and scavenger receptor in rabbit atherosclerotic lesions marked induction of scavenger receptor and VLDL receptor expression during lesion development
11. Lipid accumulation and foam cell formation in Chinese hamster ovary cells overexpressing very low density lipoprotein receptor
12. 1α.25-dihydroxyvitamin D, induces VLDL receptor mRNA expression in HL-60 cells in association with monocytic differentiation
13. The pathogenesis of atherosclerosis: A perspective for the 1990s
14. Isolation of mononuclear cells and granulocytes from human blood
15. A simple method for polyethylene glycol-promoted hybridization of mouse myeloma cells
16. Human apolipoprotein E receptor 2: A novel lipoprotein receptor of the low density lipoprotein receptor family predominantly expressed in brain
17. Human macrophage scavenger receptors: Primary structure, expression, and localization in atherosclerotic lesions
18. Protein measurement with the Folin phenol reagent
19. Single-step method of RNA isolation by acid guanidinum thiocyanate-phenol-chloroform extraction
20. Molecular cloning and expression of the human IFN-γ receptor
21. Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein
22. The distribution and chemical composition at ultracentrifugally separated lipoproteins in human serum
23. Metabolism of cationized lipoproteins by human fibroblasts
24. Regional accumulations of T cells, macrophages, and smooth muscle cells in the human atherosclerotic plaque
25. A receptor-mediated pathway for cholesterol homeostasis
26. Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition
27. Receptor-mediated uptake of remnant lipoproteins by cholesterol-loaded human monocyte-macrophages
28. Increased frequency of lipoprotein disorders similar type III hyperlipoproteinemia in survivors of myocardial infarction in Japan
29. Intermediate-density lipoproteins and progression of coronary artery disease in hypercholesterolaemic men
30. Plasma lipoproteins and progression of coronary artery disease evaluated by angiography and clinical events
31. Multiple processes are involved in the uptake of chylomicron remnants by mouse peritoneal macrophages
32. Suppression of aortic atherosclerosis in cholesterol-fed rabbits by purified rabbit interferon
33. The effects of total lymphocyte deficiency on the extent of atherosclerosis in apoE -/- mice
34. Interferon-γ inhibits arterial stenosis after injury
35. IFN-γ inhibits scavenger receptor expression and foam cell in human monocyte-derived macrophages
36. Immune IFN inhibits proliferation and induces 2′-5′-oligoadenylate synthetase gene expression in human vascular smooth muscle cells
37. IFN-γ inhibits both smooth muscle cell proliferation and expression of differentiation-specific α-smooth muscle actin in arterial smooth muscle cells
38. An atherogenic diet rapidly induces VCAM-I, a cytokine-regulatable mononuclear leukocyte adhesion molecule, in rabbit aortic endothelium
39. Expression of class II transplantation antigen on vascular smooth muscle cells in human atherosclerosis
40. Regulation of smooth muscle cell scavenger receptor expression in vivo by atherogenic diets and in vitro by cytokines
41. IFN-γ potentiates atherosclerosis in apoE knock-out mice
42. IFN-γ elicits arteriosclerosis in the absence of leukocytes