Pyrrolidine inhibitors of human cytosolic phospholipase A2. Part 2: Synthesis of potent and crystallized 4-triphenylmethylthio derivative 'pyrrophenone'

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 4, 2001, Pages 587-590

  Eno, Kaoru ^a   Okuno, Takayuki ^a   Nishi, Koichi ^a   Murakami, Yasushi ^a   Yamada, Katsutoshi ^a   Nakamoto, Shozo ^a   Ono, Takashi ^a  

^a SHIONOGI AND CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 TRIPHENYLMETHYLTHIO DERIVATIVE; ANTIINFLAMMATORY AGENT; ARACHIDONATE 5 LIPOXYGENASE; ARACHIDONIC ACID; CALCIMYCIN; DOCEBENONE; INDOMETACIN; LACTATE DEHYDROGENASE; LEUKOTRIENE B4; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; PYRROLIDINE DERIVATIVE; PYRROPHENONE; THROMBOXANE B2; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD; CONTROLLED STUDY; CRYSTALLIZATION; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL;

ARACHIDONIC ACID; CRYSTALLIZATION; CYTOSOL; DINOPROSTONE; ENZYME INHIBITORS; HUMANS; PHOSPHOLIPASES A; PYRROLIDINES; THROMBOXANE B2;

EID: 0035952312     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00003-8     Document Type: Article

References (24)