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Volumn 11, Issue 4, 2001, Pages 571-574

Discovery of potent and selective succinyl hydroxamate inhibitors of matrix metalloprotease-3 (stromelysin-1)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; STROMELYSIN; STROMELYSIN INHIBITOR; SUCCINYLHYDROXAMIC ACID DERIVATIVE; UK 356618; UNCLASSIFIED DRUG;

EID: 0035952220     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00720-4     Document Type: Article
Times cited : (31)

References (16)
  • 4
    • 84992247989 scopus 로고    scopus 로고
    • Compound 7: Prepared from 4′-fluoro-1,1′-biphen-4-ylbutanoic acid (Esser, C. K. et al. J. Med. Chem. 1997, 40, 1026) by the method of Porter, J. R.; Beeley, N. R. A.; Boyce, B.; Mason, B.; Millican, A.; Millar, K.; Leonard, J.; Morphy, J. R.; O'Connell, J. P. Bioorg. Med. Chem. Lett. 1994, 4, 2741
  • 5
    • 84992281133 scopus 로고    scopus 로고
    • 3 (4 bar, HOAc 20 °C, 100%
  • 7
    • 84992259966 scopus 로고    scopus 로고
    • note
  • 12
    • 84992273983 scopus 로고    scopus 로고
    • 2. Enzyme and substrate concentrations were typically 1 nM and 5-10 μM respectively
  • 14
    • 84992242964 scopus 로고    scopus 로고
    • note
  • 15
    • 84992247968 scopus 로고    scopus 로고
    • note


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.