DNA interaction and cytotoxicity of a new series of indolo[2,3-b]quinoxaline and pyridopyrazino[2,3-b]indole derivatives

Chemico-Biological Interactions

Volumn 138, Issue 1, 2001, Pages 59-75

  Arimondo, Paola B ^a   Baldeyrou, Brigitte ^a   Laine, William ^a   Bal, Christine ^a   Alphonse, France Aimée ^b   Routier, Sylvain ^b   Coudert, Gérard ^b   Mérour, Jean Yves ^b   Colson, Pierre ^c   Houssier, Claude ^c   Bailly, Christian ^a  

^a INSERM   (France)

^b UNIVERSITÉ D'ORLÉANS   (France)

^c UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Cell cycle; Cytotoxicity; DNA binding; DNA intercalation; Topoisomerase II

Indexed keywords

ANTIVIRUS AGENT; DNA TOPOISOMERASE (ATP HYDROLYSING); FUNCTIONAL GROUP; INDOLE DERIVATIVE; INDOLO[2,3 B]QUINOXALINE; INTERCALATING AGENT; MITOXANTRONE; NITROGEN; PYRAZINO[2,3 B]INDOLE; PYRIDOPYRAZINO[2,3]INDOLE DERIVATIVE; QUINOXALINE DERIVATIVE; UNCLASSIFIED DRUG;

ABSORPTION; ARTICLE; BINDING AFFINITY; CELL CYCLE; CELL LINE; CHROMATOPHORE; CONTROLLED STUDY; CYTOMETRY; CYTOTOXICITY; DNA BINDING; DNA CLEAVAGE; DNA FOOTPRINTING; GC RICH SEQUENCE; HUMAN; LEUKEMIA; NONHUMAN; PROTEIN INTERACTION; PROTEIN STRUCTURE; TEMPERATURE;

ANIMALS; CATTLE; CELL CYCLE; CELL DIVISION; DNA; DNA FOOTPRINTING; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; HL-60 CELLS; HUMANS; INDOLES; INTERCALATING AGENTS; QUINOXALINES;

EID: 0035950424     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(01)00260-5     Document Type: Article

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