Efficacy and safety of tenecteplase in combination with enoxaparin, abciximab, or unfractionated heparin: The ASSENT-3 randomised trial in acute myocardial infarction

Lancet

Volumn 358, Issue 9282, 2001, Pages 605-613

  Van de Werf, F ^a   Armstrong, P W ^a   Granger, C ^a   Wallentin, L ^a   Adgey, A A J ^a   Aylward, P ^a   Binbrek, A S ^a   Califf, R ^a   Cassim, S ^a   Diaz, R ^a   Fanebust, R ^a   Fioretti, P M ^a   Huber, K ^a   Husted, S ^a   Lindahl, B ^a   Lopez Sendon J L ^a   Makijarvi M ^a   Meyer, J ^a   Navarro Robles, J ^a   Pfisterer, M ^a   Seabra Gomes, R ^a,a   Soares Piegas, L ^a   Sugrue, D ^a   Tendera, M ^a   Theroux, P ^a   Toutouzas, P ^a   Vahanian, A ^a   Verheugt, F ^a   Sarelin, H ^a   Goetz, G ^a   Bluhmki, E ^a   Daclin, V ^a   Danays, T ^a   Houbracken, K ^a   Kaye, J ^a   Reilly, P ^a   Hacke, W ^a   von Kummer, R ^a   Lesaffre, E ^a   Bogaerts, K ^a   Peeters, C ^a   Fox, K A A ^a   Brower, R ^a   Hirsh, J ^a   Maggioni, A ^a   Tijssen, J ^a   Weaver, D ^a   Beernaert, A ^a   Beysen, N ^a   Broos, K ^a   De Prins, E ^a   D'hollander K ^a   Dupon, L ^a   Fomyna, N ^a   Fransen, A ^a   Genesse, D ^a   Goffin, L ^a   Hendrickx, R ^a   Jansen, B ^a   Jorissen, F ^a   Luys, C ^a   Luyten, A ^a   Marschal, C ^a   Moreira, M ^a   Munsters, K ^a   Salerno, R ^a   Schoovaerts, C ^a   Sinnaeve, P ^a   Schildermans, C ^a   Vandenberghe, K ^a   Vandeschoot, K ^a   Van Gucht, H ^a   Van Rompaey, P ^a   Vlassak, S ^a   Watzeels, M ^a   Wittockx, H ^a   Galan, K ^b   Humeniuk, L ^b   Seidel, A ^b   Molina, M ^b   Hafley, G ^b   Alexander, J ^a,b   Pascual, A ^c   Bestilny, S ^d   Temple, T ^d   Ahuad Guerrero, R ^a   Albisu, J P ^a   Bassani Arrieta, C A ^a   Bono, J ^a   Caccavo, A ^a   Cagnolatti, A ^a   Cartasegna, L R ^a   Castellanos, R ^a   Chekerdemian, S ^a   Covelli, G ^a   Cuello, J L ^a   Cuneo, C A ^a   Fernandez, A ^a   Ferrara, C ^a   Ferro Queirel, E ^a   Gambarte, A ^a   Garcia Duran, R ^a   Hasbani, E ^a   Hrabar, A ^a   Keller, L ^a   Lobo Marquez, L L ^a   Luciardi, H ^a   Macin, S M ^a   Marinig, A ^a   Marzetti, E ^a   Muntaner, J ^a   Nordaby, R ^a   Orlandini, A D ^a   Piombo, A C ^a   Pomposiello, J C ^a   Quijano, R A ^a   Amerena, J ^a   Aroney, G ^a   Buckmaster, N ^a   Carroll, P ^a   Fitzpatrick, M ^a   Newman, R ^a   Rowe, M ^a   Singh, B ^a   Thomson, A ^a   Winter, C ^a   Eber, B ^a   Gaul, G B ^a   Klein, W ^a   Leisch, F ^a   Mayr, H ^a   Mlczoch, J ^a   Niessner, H ^a   Pachinger, O ^a   Pall, H ^a   Pichler, M ^a   Roggla G ^a   Schaflinger, E ^a   Schreiber, W ^a   Slany, J ^a   Traindl, O ^a   Zenker, G ^a   Beckers, J ^a   Bekaert, I ^a   Berthe, C ^a   Bodur, G ^a   Carlier, B ^a   Carlier, M ^a   Carpentier, J ^a   Celen, H ^a   Charlier, F ^a   Clement, A ^a   Coenen, A ^a   Crochelet, L ^a   De Keyser, F ^a   De Man, F ^a   de Meester, A ^a   Dendale, P ^a   Dhondt, E ^a   Dhooghe, G ^a   El Allaf, D ^a   Elshot, S ^a   Emmerechts, C ^a   Foret, F ^a   Gatera, E ^a   Geraedts, J ^a   Gerardy, A C ^a   Gysbrechts, M ^a   Hallemans, R ^a   Hellemans, S ^a   Herssens, H ^a   Huygens, L ^a   Janssens, L ^a   Lalmand, J ^a   Maamar, R ^a   Marechal, P ^a   Mertens, D ^a   Michel, P ^a   Morandini, E ^a   Nannan, M ^a   Nguyen, D ^a   Odeurs, W ^a   Peerenboom, P ^a   Pirenne, B ^a   Quinonez, M ^a   Raymenants, E ^a   Renard, M ^a   Silance, P G ^a   Standaert, A M ^a   Striekwold, H ^a   Thiels, H ^a   Valadi, D ^a   van Brabandt, H ^a   Van Dormael, M ^a   Van Iseghem, P ^a   Van Walleghem, U ^a   Vanden Bosch, H ^a   Vandenbossche, J L ^a   Vermylen, J ^a   Verstraete, S ^a   Vo Ngoc, P ^a   Willems, P ^a   Zenner, R ^a   Campos de Albuquerque, D ^a   Coutinho, M ^a   de Camargo Carvalho, A C ^a   Fernandes Manenti, E R ^a   Ferreira Azevedo, A ^a   Golin, V ^a   Gun, C ^a   Marin Neto, J A ^a   Marino, R L ^a   Miranda Abrantes, J A ^a   Nicolau, J C ^a   Porto Alegre Dancini, E M ^a   Rabelo, A ^a   Ramos, R F ^a   Rizzi Coelho, O ^a   Alexander, D ^a   Bata, I R ^a   Bhargava, R K ^a   Bogaty, P ^a   D'amours G ^a   Darcel, I ^a   Finnie, K J C ^a   Fowlis, R ^a   Gupta, M K ^a   Henderson, M ^a   Howlett, M K ^a   Javier, J J ^a   Kieu, C V ^a   Kumar, G ^a   Lebouthillier, P 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M ^a   Bermes, M ^a   Bernsmeier, R ^a   Bethge, K P ^a   Bethge, H ^a   Block, M ^a   Burkhardt, W ^a   Cieslinski, G ^a   Claus, G ^a   Deetjen, A ^a   Diefenbach, A ^a   Diehm, C ^a   Dietz, A ^a   Dippold, W G ^a   Eichner, A ^a   Erckenbrecht, J F ^a   Gawlick, L ^a   Gerber, V ^a   Goppel, L ^a   Gottwik, M ^a   Grosch, B ^a   Hammer, B ^a   Hanheide, M ^a   Hanrath, P ^a   Haspel, J ^a   Hennersdorf, F ^a   Hermanns, M ^a   Hoffmeister, H M ^a   Holzapfel, P ^a   Hubner H ^a   Jansen, W ^a   Jung, S ^a   Kaddatz, J ^a   Kienbock H ^a   Klein, H H ^a   Konz, K H ^a   Kulschbach M ^a   Leschke, M ^a   Liebau, G ^a   Linnartz, M ^a   Lockert, G ^a   Loesbrock, R ^a   Lollgen H ^a   Ludwig, N ^a   Mudra, H ^a   Munzer K ^a   Nebel, B ^a   Nellessen, U ^a   Neu, C ^a   Olbrich, H G ^a   Pfeffer, A ^a   Pfeiffer, P ^a   Plate, V ^a   Pollock, B ^a   Rapp, H ^a   Rommele U ^a   Sauer, K ^a   Scheffler, N ^a   Schlotterbeck, K ^a   Schmidt Salzmann, A ^a   Schnitzler, G ^a   Schumann, H ^a   Schuster, C J ^a   Schuster, P ^a   Schweizer, P ^a   Seitz, K ^a   Simon, R ^a   Spes, C ^a   Szabo, S ^a   Terhardt Kasten, E ^a   Theuerkauf, B ^a   Tigges, R ^a   Tinnappel, J ^a   Topp, H ^a   Trockel, P ^a   Unland, N ^a   Veth, V ^a   Vom Dahl, J ^a   Vossbeck, G ^a   Weindel, K ^a   Weib, D ^a   Wiewel, D ^a   Wirtz, P ^a   Zipp, C ^a   Apostolou, T ^a   Chalkidis, C ^a   Exadaktylos, N ^a   Foussas, S ^a   Hatseras, D ^a   Karas, S ^a   Karydis, K ^a   Lambrou, S ^a   Louridas, G ^a   Manolis, A ^a   Nanas, J ^a   Novas, I ^a   Panagiotidou, T ^a   Papadopoulos, C ^a   Papakonstantinou, D ^a   Papasteriadis, E ^a   Pavlidis, P ^a   Pyrgakis, V ^a   Skoufas, P ^a   Stavrati, A ^a   Tyrologos, A ^a   Vardas, P ^a   Vrouchos, G ^a   Zacharoulis, A ^a   Zarifis, J ^a   Brown, A ^a   Daly, K ^a   Fennell, W ^a   Horgan, J ^a   McCann, H ^a   McDonald, K ^a   O'reilly M ^a   Sullivan, P ^a   Altamura, G ^a   Ambrosio, G ^a   Auteri, A ^a   Aveta, P ^a   Azzarito, M ^a   Badano, L P ^a   Barbiero, M ^a   Barletta, C ^a   Biscosi, C ^a   Boccanelli, A ^a   Bottero, M ^a   Brizio, E ^a   Brunazzi, M C ^a   Brunelli, C ^a   Bugatti, U ^a   Capozi, A ^a   Capucci, A ^a   Carfora, A ^a   Caronna, A ^a   Carrone, M ^a   Casazza, F ^a   Cauticci, A ^a   Ceci, V ^a   Ciconte, V ^a   Circo, A ^a   Ciricugno, S ^a   Comito, F ^a   Cornacchia, D ^a   Corsini, G ^a   D'andrea F ^a   De Rosa, P ^a   De Simone, M ^a   Del Citerna, F ^a   Del Pinto, M ^a   Dell'ali C ^a   Della Casa, S ^a   Della Monica, R ^a   Delogu, G ^a   Di Biase, M ^a   Di Chiara, A ^a   Di Guardo, G ^a   Di Marco, S ^a   Di Mario, F ^a   Di Napoli, T ^a   Di Palma, F ^a   Fadin, B M ^a   Fazzari, M ^a   Ferraiuolo, G ^a   Fiaschetti, R ^a   Fontanelli, A ^a   Fresco, C ^a   Gambelli, G ^a   Gasbarri, F ^a   Gemelli, M ^a   Giani, P ^a   Gigantino, A ^a   Giomi, A ^a   Giorgi, G ^a   Greco, C ^a   Gregorio, G ^a   Guagnozzi, G ^a   Guiducci, U ^a   Guzzardi, G ^a   Izzo, A ^a   La Rosa, A ^a   Leone, F 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  Martinez A ^a   Mendoza, M ^a   Moguel, R ^a   Navarro, J ^a   Portos, J M ^a   Rodriguez I ^a   Sierra, L ^a   Valencia, S ^a   Vazquez A ^a   Arnold, A E R ^a   Boehmer, A G ^a   de Graaf, J J ^a   Funke Kupper A J ^a   Gobel E J A M ^a   Janus, C L ^a   Linssen, G C M ^a   Sedney, M I ^a   Slegers, L C ^a   Spierenburg, H A M ^a   Strikwerda, S ^a   Tans, J G M ^a   Twisk, S P M ^a   van der Heijden, R ^a   van Kalmthout, P M ^a   Verheugt, F W A ^a   Holt, E ^a   Skogsholm, A ^a   Thorshaug, R ^a   Thybo, N K ^a   Wang, H ^a   Maciejewicz, J ^a   Piotrowski, W ^a   Pluta, W ^a   Ruminski, W ^a   Skura, M ^a   Smielak Korombel W ^a   Carranca, J ^a   Carvalho, M ^a   Catarino, C ^a   Cunha, D ^a   Ferreira, D ^a   Ferreira, J ^a   Ferreira da Costa, A F ^a   Lopes de Carvalho, J ^a   Martins, L ^a   Mourao, L ^a   Oliveira Carrageta, M ^a   Prazeres de Sa, E ^a   Puig, J ^a   Ramalho Dos Santos, M J J ^a   Baig, M M E ^a   Bayat, J ^a   Benjamin, J D ^a   Ranjith, N ^a   Routier, R ^a   Wittmer, H ^a   Abizanda Campos, R ^a   Alonso Garcia, M A ^a   Amaro Cendon, A ^a   Arboleda Sanchez, J A ^a   Blanco Varela, J ^a   Bruguera I Cortada, J ^a   Carpintero Avellaneda, J L ^a   Caturla Such, J ^a   Civeira Murillo, E ^a   Fernandez Aviles, F ^a   Fernandez Fernandez, R ^a   Figueras Bellot, J ^a   Fiol Sala, M ^a   Froufe Sanchez, J ^a   Garcia Calabozo, R ^a   Garcia Palacios, J L ^a   Gonzalez Maqueda, I ^a   Kallmeyer Martin, C ^a   Manzano Ramirez, A ^a   Marine Rebull, J ^a   Monton Rodriguez, A ^a   Pique Gilart, M ^a   Reina Toral, A ^a   Rodriguez Llorian, A ^a   Ruano Marco, M ^a   Sanchez Miralles, A ^a   Sanjose Garagarza, J M ^a   Santalo Bel, M ^a   Torres Ruiz, J M ^a   Valentin Segura, V ^a   Ahlstrom, P ^a   Ahremark, U ^a   Bandh, S ^a   Bellinetto, A ^a   Dahlberg, A ^a   Hansen, O ^a   Hurtig, U ^a   Jonasson, L ^a   Karlsson, J E ^a   Larsson, L E ^a   Moller, B ^a   Ohlin, H ^a   Persson, H ^a   Sandstedt, L ^a   Soderberg, S ^a   Svennberg, L ^a   Swahn, E ^a   Tygesen, H ^a   Broccard, A F ^a   Estlinbaum, W ^a   Follath, F ^a   Frutiger, A ^a   Hess, N ^a   Maggiorini, M ^a   Marti, D ^a   Muller P ^a   Rickenbacher, P ^a   Schaller, M D ^a   Weinbacher, M ^a   Abdulali, S ^a   Ahmad, G ^a   George, S ^a   Ghazi, A ^a   Rao, K N ^a   Bishop, A ^a   Bridges, A ^a   Canepa Anson, R ^a   Cave, M ^a   Clarck, R ^a   Cooper, I ^a   de Belder, A ^a   Farrer, M ^a   Kendall, J M ^a   Ludman, P ^a   Mattu, R ^a   McGlinchey, P ^a   Moriarty, A J ^a   Muthusamy, S ^a   Nee, P A ^a   Nolan, J ^a   Papouchado, M ^a   Rose, E L ^a   Shahi, M ^a   Stephens, J ^a   Trevelyan, J ^a   Abdul Karim, A ^a   Adler, L ^a   Arunasalam, S ^a   Avington, D ^a   Baron, S ^a   Beel, T ^a   Bellamy, B ^a   Bennett, J ^a   Berndt, T ^a   Berrick, A ^a   Bersin, R M ^a   Bethala, V ^a   Bharath, S ^a   Bouchard, A ^a   Boulet, J E ^a   Bowerman, R ^a   Boyek, T ^a   Brar, R S ^a   Brodell, G ^a   Bryant, B ^a   Buckner, J K ^a   Cage, J ^a   Cannon, J D ^a   Carducci, B ^a   Carr, K ^a   Chang, M ^a   Chelliah, N ^a   Chin, W L ^a   Chin, J ^a   Church, D H ^a   Clark, R ^a   Coulis, L ^a   Dadkhah, S ^a   Dearing, B ^a   Defranco, A ^a   Dharawat, M ^a   Dharawat, R ^a   Dhruva, N ^a   Dicola, J ^a   Dykstra, G ^a   Eisenberg, S ^a   El Bialy, A ^a   Fera, S ^a   Ford, K ^a   Foreman, R D ^a   Friedman, S ^a   Friedman, V ^a   Garibian, G ^a   Gelormini, J ^a   Geninatti, M R ^a   Genovese, R ^a   Ghazi, F ^a   Gilchrist, I ^a   Gitler, B ^a   Glover, R ^a   Gonzalez, J ^a   Goulah, R ^a   Graham, B ^a   Gray, R ^a   Grodman, R ^a   Habib, G B ^a   Hack, T ^a   Hamroff, G ^a   Hanna, G ^a   Hart, M ^a   Haught, H ^a   Hawkins, J ^a   Hempel, R ^a   Hiremath, Y ^a   Hiser, W ^a   Holland, E ^a   Jaffe, N ^a   Jamal, N ^a   James, K F ^a   Kalla, S ^a   Kates, M ^a   Kemper, A J ^a   Kennedy, J J ^a   Kerut, E K ^a   Killpack, M ^a   King, J ^a   Ko, T Y ^a   Kollar, K ^a   Kontos, M ^a   Kugelmassluu, A ^a   Kumar, A ^a   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F ^a   Ryman, K ^a   Salacata, A ^a   Santolin, C ^a   Saucedo, J ^a   Savage, R ^a   Savage, W ^a   Schumacher, R ^a   Segarra, S ^a   Sharkey, S ^a   Shonkoff, D ^a   Silver, M ^a   Silver, S L ^a   Singh, G ^a   Sinyard, R D ^a   Sporn, D ^a   Srivastava, N K ^a   Stomel, R ^a   Suresh, D P ^a   Tallman, M ^a   Togioka, T ^a   Varma, S ^a   Verant, R P ^a   Wallach, R ^a   Weinberg, M ^a   Weinberg, D ^a   Weinstein, J M ^a   Wesley, G ^a   Westerman, J H ^a   Wheeling, J ^a   Whitaker, J ^a   Widmer, M ^a   Yasin, M ^a   Zakrzewski, M J ^a   more..

^a Duke Clinical Research Institute ^*  (United States)

^b DUKE CLINICAL RESEARCH INSTITUTE   (United States)

^c Estudios Clinicos Latinoamerica   (Argentina)

^d UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ABCIXIMAB; ACETYLSALICYLIC ACID; ANGIOTENSIN II ANTAGONIST; ANTICOAGULANT AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CLOPIDOGREL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENOXAPARIN; FIBRINOGEN RECEPTOR ANTAGONIST; FIBRINOLYTIC AGENT; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN; NITRATE; PYRIDINE DERIVATIVE; STATIN; TENECTEPLASE; THIENOPYRIDINE; TICLOPIDINE; UNCLASSIFIED DRUG;

ACUTE HEART INFARCTION; ADULT; AGED; ARTICLE; BLEEDING; BODY WEIGHT; BRAIN HEMORRHAGE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; FEMALE; HEART REINFARCTION; HOSPITAL ADMISSION; HOSPITAL DISCHARGE; HUMAN; ISCHEMIA; MAJOR CLINICAL STUDY; MALE; MORTALITY; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REPERFUSION; ST SEGMENT ELEVATION; STROKE; THROMBOCYTOPENIA;

EID: 0035949117     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(01)05775-0     Document Type: Article

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