Alanine-scanning Mutagenesis of Plasmatocyte Spreading Peptide Identifies Critical Residues for Biological Activity

Journal of Biological Chemistry

Volumn 276, Issue 21, 2001, Pages 18491-18496

  Clark, Kevin D ^a   Volkman, Brian F ^b   Thoetkiattikul, Honglada ^a   King, David ^b   Hayakawall, Yoichi ^c   Strand, Michael R ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOASSAY; CELL CULTURE; GROWTH KINETICS; IMMUNOLOGY; MOLECULAR STRUCTURE; MUTAGENESIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

BIOACTIVITY; PLASMATOCYTES;

BIOCHEMISTRY;

ALANINE; ASPARTIC ACID; CYSTEINE; CYTOKINE; EPIDERMAL GROWTH FACTOR; MUTANT PROTEIN; PHENYLALANINE; PLASMATOCYTE SPREADING PEPTIDE; THROMBOMODULIN; UNCLASSIFIED DRUG; PEPTIDE; PLASMATOCYTE SPREADING PEPTIDE 1; PLASMATOCYTE-SPREADING PEPTIDE 1;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BETA SHEET; CARBOXY TERMINAL SEQUENCE; DISULFIDE BOND; GENE DELETION; HYDROPHOBICITY; IMMUNOCOMPETENT CELL; INSECT CELL; MUTAGENESIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLASMA CELL; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN TERTIARY STRUCTURE; WILD TYPE; ANIMAL; GENETICS; INSECT; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

ANIMALIA; INSECTA;

ALANINE; ANIMALS; BASE SEQUENCE; INSECTS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDES; POINT MUTATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035947644     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M100579200     Document Type: Article

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