Follistatin: Essential Role for the N-terminal Domain in Activin Binding and Neutralization

Journal of Biological Chemistry

Volumn 276, Issue 21, 2001, Pages 17718-17726

  Sidis, Yisrael ^a   Schneyer, Alan L ^a   Sluss, Patrick M ^a   Johnson, Leslie N ^a   Keutmann, Henry T ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; CELLS; CHEMICAL MODIFICATION; HORMONES; MUTAGENESIS; TISSUE;

BIOACTIVITY; MUTATIONS;

PROTEINS;

ACTIVIN; ALANINE; ARGININE; ASPARTIC ACID; CYSTEINE; DISULFIDE; FOLLISTATIN; FOLLITROPIN; LYSINE; SCLEROPROTEIN; TRYPTOPHAN; GLYCOPROTEIN; INHIBIN; RECOMBINANT PROTEIN;

ADENOHYPOPHYSIS; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BIOASSAY; CELL CULTURE; CELL DIFFERENTIATION; CELL SECRETION; CHEMICAL MODIFICATION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GENE MUTATION; GENETIC TRANSCRIPTION; HORMONE RELEASE; HYDROPHOBICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CHO CELL; GENETICS; HAMSTER; HUMAN; METABOLISM; MOLECULAR GENETICS; MUTATION; STRUCTURE ACTIVITY RELATION;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

ACTIVINS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CHO CELLS; CRICETINAE; FOLLISTATIN; GLYCOPROTEINS; HUMANS; INHIBINS; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035947603     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M100736200     Document Type: Article

References (50)

1. Vale, W., Rivier, C., Hsueh, A., Campen, C., Meunier, H., and Bicsak, T. (1988) Recent Prog. Horm. Res. 44, 1-34
2. Michel, U., Farnworth, P., and Findlay, J. K. (1993) Mol. Cell. Endocrinol. 91, 1-11
3. DePaolo, L. V. (1997) Proc. Soc. Exp. Biol. Med. 214, 328-339
4. Peng, C., and Mukai, S. T. (2000) Biochem. Cell Biol. 78, 261-279
5. Shimasaki, S., Koga, M., Esch, F., Cooksey, K., Mercado, M., Koba, A., Ueno, N., Ying, S.-Y., Ling, N., and Guilleman, R. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 4218-4222
6. Nakamura, T., Takio, K., Eto, Y., Shibai, H., Titani, K., and Sugino, H. (1990) Science 247, 836-838
7. Schneyer, A. L., Rzucidlo, D. A., Sluss, P. M., and Crowley, W. F. (1994) Endocrinology 135, 667-674
8. Meriggiola, M., Dahl, K. D., Mather, J. P., and Bremner, W. J. (1994) Endocrinology 134, 1967-1970
9. deWinter, J. P., ten Dijke, P., de Vries, C. J. M., van Achterberg, T. A. E., Sugino, H., de Waele, P., Huylebroeck, D., Verschueren, K., and van den Eijnden-van Raaij, A. J. M. (1996) Mol. Cell. Endocrinol. 116, 105-114
10. Hashimoto, O., Nakamura, T., Shoji, H., Shimasaki, S., Hayashi, Y., and Sugino, H. (1997) J. Biol. Chem. 272, 13835-13842
11. Inouye, S., Ling, N., and Shimasaki, S. (1992) Mol. Cell. Endocrinol. 90, 1-6
12. Matzuk, M. M., Llu, N., Vogel, H., Sellheyer, K., Roop, D. R., Jaenisch, R., and Bradley, A. (1995) Nature 374, 360-363
13. Patthy, L., and Nikolies, K. (1993) Trends Neurosci. 16, 76-81
14. Hohenester, E., Maurer, P., and Timpl, R. (1997) EMBO J. 16, 3778-3786
15. Yan, Q., and Sage, E. H. (1999) J. Histochem. Cytochem. 47, 1495-1505
16. Uchida, T., Wada, K., Akamatsu, T., Yonezawa, M., Noguchi, H., Mizoguchi, A., Kasuga, M., and Sakamoto, C. (1999) Biochem. Biophys. Res. Commun. 20, 593-602
17. Tsuchida, K., Arai, K. Y., Kuramoto, Y., Yamakawa, N., Hasegawa, Y., and Sugino, H. (2000) J. Biol. Chem. 275, 40788-40796
18. Wang, Q. F., Keutmann, H. T., Schneyer, A. L., and Sluss, P. M. (2000) Endocrinology 141, 3183-3193
19. Inouye, S., Guo, Y., Ling, N., and Shimasaki, S. (1991) Biochem. Biophys. Res. Commun. 179, 352-358
20. Gray, P. C., Greenwald, J., Blount, A. L., Kunitake, K. S., Donaldson, C. J., Choe, S., and Vale, W. (2000) J. Biol. Chem. 275, 3206-3212
21. Wang, Q. F., Khoury, R. H., Smith, P. C., McConnell, D. S., Padmanahban, V., Midgley, A. R., Schneyer, A. L., Crowley, W. F., and Sluss, P. M. (1996) J. Clin. Endocrinol. Metab. 81, 1434-1441
22. Delbaere, A., Sidis, Y., and Schneyer, A. L. (1999) Endocrinology 140, 2463-2470
23. McConnell, D. S., Wang, Q. F., Sluss, P. M., Bolf, N., Khoury, R. H., Schneyer, A. L., Midgley, A. R., Reame, N. E., Crowley, W. F., and Padmanabhan, V. (1998) J. Clin. Endocrinol. Metab. 83, 851-858
24. Scott, R. S., Burger, H. G., and Quigg, H. (1980) Endocrinology 107, 1536-1542
25. Neuman, N. P., Moore, S., and Stein, W. H. (1962) Biochemistry 1, 68-75
26. Purnananda, G., Balasubramanian, D., Matsugo, S., and Saito, I. (1992) Biochemistry 31, 4296-4303
27. Dyson, H. J., Merutka, G., Waltho, J. P., Lerner, R. A., and Wright, P. E. (1992) J. Mol. Biol. 226, 795-817
28. Clackson, T., and Wells, J. A. (1995) Science 267, 383-386
29. Greenwald, J., Fischer, W. H., Vale, W. W., and Choe, S. (1999) Nat. Struct. Biol. 6, 18-22
30. Wuytens, G., Verschueren, K., deWinter, J. P., Gajendran, N., Beek, L., Devos, K., Bosman, F., de Waele, P., Andries, M., van den Eijnden-van Raaij, A. J. M., Smith, J. C., and Huylebroeck, D. (1999) J. Biol. Chem. 274, 9821-9827
31. Hayette, S., Gadoux, M., Martel, S., Bertrand, S., Tigaud, I., Magaud, J.-P., and Rimokh, R. (1998) Oncogene 16, 2949-2954
32. Schneyer, A., Tortoiello, D., Sidis, Y., Keutmann, H., Matsuzaki, T, and Holmes, W. (2001) Mol. Cell. Endocrinol., in press
33. Lane, T. F., and Sage, E. H. (1990) J. Cell Biol. 111, 3065-3076
34. Kupprion, C., Motamed, K., and Sage, E. H. (1998) J. Biol. Chem. 273, 29635-29640
35. Busch, E., Hohenester, E., Timpl, R., Paulsson, M., and Maurer, P. (2000) J. Biol. Chem. 275, 25508-25515
36. Alliel, P. M., Perin, J.-P., Jolles, P., and Bonnet, F. J. (1993) Eur. J. Biochem. 214, 347-350
37. Tsen, G., Halfter, W., Kroger, S., and Cole, G. J. (1995) J. Biol. Chem. 270, 3392-3399
38. Eib, D. W., and Martens, G. J. M. (1996) J. Neurochem. 67, 1047-1055
39. Denzer, A. J., Schulthess, T., Fauser, C., Schumacher, B., Kammerer, R. A., Engel. J., and Ruegg, M. A. (1998) EMBO J. 17, 335-343
40. Burgess, R. W., Skarnes, W. C., and Sanes, J. R. (2000) J. Cell Biol. 151, 41-52
41. Yamashita, H., ten Dijke, P., Huylebroeck, D., Kuber-Sampath, T., Andries, M., Smith, J. C., Heldin, C.-H., and Miyazono, K. (1995) J. Cell Biol. 130, 217-226
42. Fainsod, A., Deissler, K., Yelin, R., Marom, K., Epstein, M., Pillemer, G., Steinbeisser, H., and Blum, M. (1997) Mech. Devel. 63, 39-50
43. Iemura, S.-I., Yamamoto, T., Takagi, C., Uchiyama, H., Natsume, T., Shimasaki, S., Sugino, H., and Ueno, N. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 9337-9342
44. Iemura, S.-I., Yamamoto, T. S., Takagi, C., Kobayashi, H., and Ueno, N. (1999) J. Biol. Chem. 274, 26843-26849
45. Gamer, L. W., Wolfman, N. M., Celeste, A. J., Hattersley, G., Hewick, R., and Rosen, V. (1999) Devel. Biol. 208, 222-232
46. Federman, S., Chen, T., Gamer, M., Wolfman, N., and Celeste, A. (2000) in Proc. 22d Annual Meeting, Am. Soc. Bone Mineral Res., Toronto, Abstr. M023
47. Haaijman, A., D'Souza, R. N., Bronckers, A. L., Goei, S. W., and Burger, E. H. (1997) J. Bone Mineral Res. 12, 1815-1823
48. Wozney, J. M., and Rosen, V. (1998) Clin. Orthop. 346, 26-37
49. Wang, Q. F., Dattatreyamurty, B., and Sluss, P. M. (2000) Int. Conf. Bone Morphogenetic Prots, Lake Tahoe, CA, p. 30 (abstr.)
50. Huang, H-J., Wu, J. C., Su, P., Zhirnov, O., and Miller, W. L. (2001) Endocrinology, in press