Inhibition of calcium-stimulated ATPase in the hen brain P2 synaptosomal fraction by organophosphorus esters: Relevance to delayed neuropathy

Journal of Toxicology and Environmental Health - Part A

Volumn 63, Issue 2, 2001, Pages 101-113

  Barber, D ^a   Hunt, J ^a   Ehrich, Marion ^a  

^a VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); ADENOSINE TRIPHOSPHATE; CALCIUM; CHLORPYRIFOS; DYFLOS; MEMBRANE LIPID; ORGANOPHOSPHATE; PARAOXON; PARATHION; PHENYLSALIGENIN PHOSPHATE; PURINE P2 RECEPTOR; SALIGENIN; TRI ORTHO CRESYL PHOSPHATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; COMPETITIVE INHIBITION; CONTROLLED STUDY; DOSE RESPONSE; ENZYME INHIBITION; FEMALE; HEN; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; NEUROPATHY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SYNAPTOSOME; TOXICOKINETICS;

ANALYSIS OF VARIANCE; ANIMALS; BRAIN; CA(2+) MG(2+)-ATPASE; CHICKENS; CHLORPYRIFOS; CHOLINESTERASE INHIBITORS; FEMALE; LINEAR MODELS; MEMBRANE LIPIDS; NEUROTOXICITY SYNDROMES; ORGANOPHOSPHORUS COMPOUNDS; RANDOM ALLOCATION; SYNAPTOSOMES;

ANIMALIA;

EID: 0035947484     PISSN: 15287394     EISSN: None     Source Type: Journal    
DOI: 10.1080/15287390151126423     Document Type: Article

References (29)

1. Abou-Donia, M. B., and Lapadula, D. M. 1990. Mechanism of organophosphorus ester induced delayed neurotoxicity; type I and type II. Annu. Rev. Pharmacol. Toxicol. 30:405-440.
2. 2+-pump activity by membrane fluidity. Biochemistry 23:4714-4720.
3. 2+-pump activity of sarcoplasmic reticulum. Pestic. Biochem. Physiol. 17:185-190.
4. Blasiak, J. 1993. Parathion and methylparathion-altered fluidity of native and model membranes. Pestic. Biochem. Physiol. 45:72-80.
5. 2+)-ATPase by the organophosphorous insecticides parathion and methylparathion. Comp. Biochem. Physiol. 110C:119-125.
6. ow) of 61 organophosphorus and carbamate insecticides and their relationship to respective water solubility (S) values. Environ. Sci. Health B18:667-683.
7. Brown, H. R., and Sharma, R. P. 1976. Synaptosornal adenosine triphosphatase (ATPase) inhibition by organophosphates. Experientia 32:1540-1542.
8. Capodicasa, E., Scapellato, M., Moretto, A., Caroldi, S., and Lotti, M. 1991. Chlorpyrifos-induced delayed neuropathy. Arch. Toxicol. 65:150-155.
9. Carafoli, E., and Stauffer, T. 1994. The plasma membrane calcium pump: Functional domains, regulation of the activity, and tissue specificity of isoform expression. J. Neurobiol. 25:312-324.
10. Cavanagh, J. B. 1954. Peripheral nerve changes in ortho-cresyl phosphate poisoning in the cat. J. Pathol. Bacteriol. 87:365-383.
11. Clegg, D. J., and van Gemert, M. 1999. Expert panel report of human studies on chlorpyrifos and/or other organophosphate exposures. J. Toxicol. Environ. Health B 2:257-279.
12. Clothier, B., and Johnson, M. K. 1980. Reactivation and aging of neurotoxic esterase inhibited by a variety of organophosphorus esters. Biochem. J. 185:731-747.
13. 2+)-ATPase in sorghum (Sorghum bicolor L.), Pestic. Biochem. Physiol. 34:118-125.
14. Ehrich, M., and Jortner, B. In press. Organophosphorus-ester induced delayed neuropathy. In Handbook of pesticide toxicology, ed. R. Krieger, New York: Academic Press.
15. Ehrich, M., Jortner, B., and Padilla, S. 1995. Comparison of the relative inhibition of acetylcholinesterase and neuropathy target esterase in rats and hens given cholinesterase inhibitors. Fundam. Appl. Toxicol. 24:94-101.
16. Ehrich, M., Correll, L., and Veronesi, B. 1997. Acetylcholinesterase and neuropathy target esterase inhibitions in neuroblastoma cell to distinguish organophosphorus compounds causing acute and delayed neurotoxicity. Fundam. Appl. Toxicol. 38:55-63.
17. El-Fawal, H. A. N., Correll, L., Gay, L., and Ehrich, M. 1990. Protease activity in brain, nerve, and muscle of hens given neuropathy-inducing organophosphates and a calcium channel blocker. Toxicol. Appl. Pharmacol. 103:133-142.
18. Henderson, J. D., Higgins, R. J., Daccre, J. C., and Wilson, B. W. 1992. Neurotoxicity of acute and repeated treatments of tabun, paraoxon, diisopropyl fluorophosphate and isofenphos to the hen. Toxicology 72:117-129.
19. LoPachin, P. M., Lapadula, D., and Abou-Donia, M. B. 1988. Organophosphate intoxication alters distribution of elements in chicken peripheral axons. Soc. Neurosci. Abstr. 14:775.
20. Lowry, O. H., and Lopez, J. A. 1946. The determination of inorganic phosphate in the presence of labile phosphate esters. J. Biol. Chem. 162:421-429.
21. 1. Pestic. Biochem. Physiol. 30:155-165.
22. 2+-transport ATPases in different tissues. Biochem. J. 261:655-660.
23. Murphy, A. J., and Coll, R. J. 1992. Fluoride is a slow, tight-binding inhibitor of the calcium ATPase of sarcoplasmic reticulum. J. Biol. Chem. 267:5229-5235.
24. Pope, C. N. 1999. Organophosphorus pesticides: do they all have the same mechanism of toxicity? J. Toxicol. Environ. Health B 2:161-181.
25. Richardson, R. 1995. Assessment of the neurotoxic potential of chlorpyrifos relative to other organophosphorus compounds: A critical review of the literature. J. Toxicol. Environ. Health 44: 135-165.
26. ++ pump activities during organophosphorus-ester-induced delayed neurotoxicity development period. J. Biochem. Toxicol. 10:233-238.
27. Sorensen, R. G., and Mahler, H. R. 1981. Calcium-stimulated adenosine triphosphatases in synaptic membranes. J. Neurochem. 37:1407-1418.
28. Suwita, E., Lapadula, D., and Abou-Donia, M. B. 1986. Calcium and calmodulin stimulated in vitro phosphorylation of rooster brain tubulin and MAP-2 following a single oral dose of tri-o-cresyl phosphate. Brain Res. 374:199-203.
29. U.S. Environmental Protection Agency. 1991. Pesticide Assessment Guidelines, Subdivision E. Hazard Evaluation: Human and Domestic Animals. [Addendum 10: Neurotoxicity, series 81, 82, and 83]. Office of Prevention, Pesticides, and Toxic Substances, Washington, DC. EPA 540/09-1-123. Available from NTIS, Springfield, VA, PB91-154617.