Clinical and echocardiographic follow-up of patients previously treated with dexfenfluramine or phentermine/fenfluramine

JAMA

Volumn 286, Issue 16, 2001, Pages 2011-2014

  Gardin, Julius M ^a,e   Weissman, Neil J ^b   Leung, Cyril ^a   Panza, Julio A ^c   Fernicola, Daniel ^b   Davis, Kelly D ^d   Constantine, Ginger D ^d   Reid, Cheryl L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b WASHINGTON HOSPITAL CENTER   (United States)

^c NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^d WYETH AYERST RESEARCH   (United States)

^e ST JOHN HOSPITAL AND MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEXFENFLURAMINE; FENFLURAMINE; PHENTERMINE;

ADULT; AGED; AORTA VALVE REGURGITATION; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE ASSOCIATION; ECHOCARDIOGRAPHY; FEMALE; FOLLOW UP; HEART EJECTION FRACTION; HEART VALVE REGURGITATION; HEART VALVE SURGERY; HUMAN; LUNG ARTERY PRESSURE; MAJOR CLINICAL STUDY; MALE; MITRAL VALVE REGURGITATION; PRIORITY JOURNAL; STATISTICAL ANALYSIS;

EID: 0035944519     PISSN: 00987484     EISSN: None     Source Type: Journal    
DOI: 10.1001/jama.286.16.2011     Document Type: Article

References (12)

1. Regression of heart-valve abnormalities after discontinuation of dexfenfluramine treatment
2. Echocardiographic improvement over time after cessation of use of fenfluramine and phentermine
3. Serial echocardiographic and clinical evaluation of valvular regurgitation before, during, and after treatment with fenfluramine or dexfenfluramine and mazindol or phentermine
4. Natural history of valvular regurgitation 1 year after discontinuation of dexfenfluramine therapy
5. Valvular abnormalities and cardiovascular status in patients following exposure to dexfenfluramine or phentermine/fenfluramine
6. Evaluation of aortic insufficiency by Doppler color flow mapping
7. Color Doppler assessment of mitral regurgitation with orthogonal planes
8. Severe aortic regurgitation from systemic hypertension (without aortic dissection) requiring aortic valve replacement
9. Prevalence and determinants of valvulopathy in patients treated with dexfenfluramine
10. Fenfluramine and phentermine and cardiovascular findings
11. Prevalence and correlates of aortic regurgitation in American Indians
12. The progression of fenfluramine-associated valvular heart disease assessed by echocardiography