Enantioselective syntheses of dopaminergic (R)- and (S)-benzyltetrahydroisoquinolines

Journal of Medicinal Chemistry

Volumn 44, Issue 11, 2001, Pages 1794-1801

  Cabedo, N ^a   Andreu, I ^a   Ramirez de Arellano, C M ^a   Chagraoui, A ^b   Serrano, A ^a   Bermejo, A ^a   Protais, P ^b   Cortes, D ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

^b UFR Medecine Pharmacie   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLTETRAHYDROISOQUINOLINE DERIVATIVE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE RECEPTOR; DOPAMINE RECEPTOR STIMULATING AGENT; TETRAHYDROISOQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BIOASSAY; CHIRALITY; DOPAMINERGIC SYSTEM; DRUG SYNTHESIS; ENANTIOMER; MALE; NONHUMAN; OPTICAL ROTATION; RAT; REDUCTION; STEREOCHEMISTRY; STEREOISOMERISM; X RAY ANALYSIS;

(R)-2,3,4,5-TETRAHYDRO-8-CHLORO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL; ANIMALS; BENZYL COMPOUNDS; BINDING, COMPETITIVE; CORPUS STRIATUM; CRYSTALLOGRAPHY, X-RAY; DOPAMINE; DOPAMINE ANTAGONISTS; ISOQUINOLINES; LIGANDS; MALE; RACLOPRIDE; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SYNAPTOSOMES;

EID: 0035942519     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm001128u     Document Type: Article

References (22)

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