Differential expression of GAD65 and GAD67 during the development of the rat retina

Brain Research

Volumn 919, Issue 2, 2001, Pages 242-249

  Dkhissi, Ouria ^a   Julien, Jean François ^b   Wasowicz, Marguerite ^a   Dalil Thiney, Najet ^c   Nguyen Legros, Jeanine ^a   Versaux Botteri, Claudine ^a,c  

^a INSERM   (France)

^b CNRS   (France)

^c MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

Author keywords

Development; GAD65; GAD67; Immunohistochemistry; Rat; Retina; RT PCR

Indexed keywords

4 AMINOBUTYRIC ACID; GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE 65; GLUTAMATE DECARBOXYLASE 67; GLUTAMIC ACID; MESSENGER RNA; PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SYNTHESIS; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; CONTROLLED STUDY; ENZYME ASSAY; EXON; GABAERGIC SYSTEM; GENETIC TRANSCRIPTION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; NERVE CELL; NEWBORN; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RETINA AMACRINE CELL; RETINA DEVELOPMENT; RETINA HORIZONTAL NERVE CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AGING; AMACRINE CELLS; ANIMALS; CELL DIFFERENTIATION; EXONS; GAMMA-AMINOBUTYRIC ACID; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLUTAMATE DECARBOXYLASE; IMMUNOHISTOCHEMISTRY; ISOENZYMES; NEURONS; RATS; RATS, WISTAR; RETINA; RETINAL GANGLION CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 0035940743     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)03022-0     Document Type: Article

References (34)

1. Free gamma-aminobutyric acid in brain
2. Analysis of the anatomical distribution of GAD67 mRNAs encoding truncated glutamic decarboxylase protein in the embryonic rat brain
3. Neurite outgrowth-regulating properties of GABA and the effect of serum on mouse spinal cord neurons in culture
4. Developmentally regulated expression of an exon containing a stop codon in the gene for glutamic decarboxylase
5. Two human glutamate decarboxylases, 65-kDa GAD and 67-kDa GAD, are each encoded by a single gene
6. GABA-like immunoreactivity in the cat retina: Electron microscopy
7. The structural and functional heterogenity of glutamic acid decarboxylase: A review
8. Two genes encode distinct glutamate decarboxylases
9. Different distributions of GAD65 and GAD67 mRNAs suggest that the two glutamate decarboxylases play distinctive functional roles
10. GABA-like immunoreactivity in the monkey retina
11. High levels of extracellular glutamate are present in retina during neonatal development
12. Cellular degeneration and synaptogenesis in the developping retina of the rat
13. GABA and histogenesis in fetal and neonatal mouse brain lacking both the isoforms of glutamic acid decarboxylase
14. Regional differences in GABA and GAD immunoreactivity in rabbit horizontal cells
15. Rat brain glutamic acid decarboxylase sequence deduced from a cloned cDNA
16. Two forms of the gamma-aminobutyric acid synthetic enzyme glutamate decarboxylase have distinct intraneuronal distributions and cofactor interactions
17. Expression of two forms of glutamic acid decarboxylase (GAD67 and GAD65) during postnatal development of rat somatosensory barrel cortex
18. Cloning and sequence analysis of a murine cDNA encoding glutamate decarboxylase (GAD65)
19. Regulatory properties of brain glutamate decarboxylase (GAD): The apoenzyme of GAD is principally as the smaller of two molecular form of GAD in brain
20. Cofactor interactions and the regulation of glutamate decarboxylase activity
21. Neurotransmitters in the regulation of neuronal cytoarchitecture
22. Kainic acid lesioning alters outer plexiform layer development in neonatal rabbit retina
23. The role of GABA during development of the outer retina in the rabbit
24. Uniqueness and redundancy in GABA production
25. GABA-Its role and development in the retina
26. Increased intracellular gamma-aminobutyric acid selectively lowers the level of the larger of two glutamate decarboxylase proteins in cultured GABAergic neurons from rat cerebral cortex
27. Gamma-aminobutyric acid in brain: Its formation from glutamic acid
28. Horizontal cells of the mouse retina contain glutamic acid decarboxylase-like immunoreactivity during early developmental stage
29. Postnatal development of a GABA deficit and disturbance of neural functions in mice lacking GAD65
30. Distinct protein forms are produced from alternatively spliced bicistronic glutamic acid decarboxylase mRNAs during development
31. Maturation postanatale des cellules horizontales de la rétine de rat
32. Immunohistochemical localization of GABA-containing neurons during postnatal development of the rat retina
33. The GABA paradox: Multiple roles as metabolite, neurotransmitter, and neurodifferentiative agent
34. GABAergic system in the developing mamalian retina: Dual sources of GABA at early stages of postnatal development