HIV in the brain: RNA levels and patterns of zidovudine resistance

Neurology

Volumn 57, Issue 8, 2001, Pages 1396-1401

  McClernon, D R ^a   Lanier, R ^a   Gartner, S ^b   Feaser, P ^b   Pardo, C A ^b   St Clair, M ^a   Liao, Q ^a   McArthur, J C ^b,c  

^a GLAXOSMITHKLINE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; DIDANOSINE; LAMIVUDINE; RNA DIRECTED DNA POLYMERASE; STAVUDINE; VIRUS RNA; ZALCITABINE; ZIDOVUDINE;

ARTICLE; AUTOPSY; CLINICAL ARTICLE; CONTROLLED STUDY; DEMENTIA; DRUG EXPOSURE; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; LYMPHOCYTE COUNT; MACROPHAGE ACTIVATION; NEUROLOGIC DISEASE; PRIORITY JOURNAL; VIRUS REPLICATION;

EID: 0035940620     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.57.8.1396     Document Type: Article

References (26)

1. Levels of human immunodeficiency virus type 1 RNA in cerebrospinal fluid correlate with AIDS dementia stage
2. Evaluation of human immunodeficiency virus (HIV) type 1 RNA levels in cerebrospinal fluid and viral resistance to zidovudine in children with HIV encephalopathy
3. Relationship between human immunodeficiency virus-associated dementia and viral load in cerebrospinal fluid and brain
4. Clinical-neuropathologic correlation in HIV-associated dementia
5. Quantitation of human immunodeficiency virus in brains of demented and nondemented patients with acquired immunodeficiency syndrome
6. Immunocytochemical quantitation of HIV in the brain: Correlations with HIV-associated dementia
7. Distribution of brain HIV load in AIDS
8. In vivo comparison of zidovudine resistance mutations in blood and CSF of HIV-1-infected patients
9. Reverse transcriptase sequence of paired isolates of cerebrospinal fluid and blood from patients infected with human immunodeficiency virus type 1 during zidovudine treatment
10. Presence of mutation conferring resistance to lamivudine in plasma and cerebrospinal fluid of HIV-1-infected patients
11. Reduction of HIV-1 in blood and lymph nodes following potent antiretroviral therapy and the virologic correlates of treatment failure
12. In vivo compartmentalization of human immunodeficiency virus: Evidence from the examination of pol sequences from autopsy tissue
13. Nomenclature and research case definitions for neurological manifestations of human immunodeficiency virus type-1 (HIV-1) infection
14. The AIDS dementia complex
15. Patterns of cerebral atrophy in HIV-1 infected individuals: Results of a quantitative MRI analysis
16. Cognitive performance and regional brain volume in human immunodeficiency virus type 1 infection
17. Morphology and distribution of HIV-1 gp41-positive microglia in subacute AIDS encephalitis. Pattern of involvement resembling a multisystem degeneration
18. AIDS dementia complex and HIV-1 brain infection: Clinical-virological correlations
19. Influence of risk group and zidovudine therapy on the development of HIV encephalitis and cognitive impairment in AIDS patients
20. Brain viral burden in HIV infection
21. HIV-1 proviral DNA load across neuroanatomic regions of individuals with evidence for HIV-1-associated dementia
22. High viral load in the cerebrospinal fluid and brain correlates with severity of simian immunodeficiency virus encephalitis
23. In-vivo comparison of RT inhibitor resistance patterns in paired cerebrospinal fluid and blood of HIV-1 infected patients with a novel line probe assay
24. Predominance of distinct viral genotypes in brain and lymph node compartments of HIV-1-infected individuals
25. Genotypic differences between plasma and seminal fluid HIV RNA in reverse transcriptase inhibitor experienced patients
26. The effects of protease inhibitor therapy on human immunodeficiency virus type 1 levels in semen (AIDS Clinical Trials Group protocol 850)