Development of potent and selective factor Xa inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 14, 2001, Pages 1797-1800

  Rai, Roopa ^a   Kolesnikov, Aleksandr ^a   Li, Yong ^a   Young, Wendy B ^a   Leahy, Ellen ^a   Sprengeler, Paul A ^a   Verner, Erik ^a   Shrader, William D ^a   Burgess Henry, Jana ^a   Sangalang, Joan C ^a   Allen, Darin ^a   Chen, Xi ^a   Katz, Bradley A ^a   Luong, Christine ^a   Elrod, Kyle ^a   Cregar, Lynne ^a  

^a Axys Pharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (3 BROMO 2 HYDROXY 5 METHYLPHENYL) 1H INDOLE 5 CARBOXAMIDINE; AMIDINE; ANTICOAGULANT AGENT; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 10A INHIBITOR; PLASMIN; SERINE PROTEINASE INHIBITOR; THROMBIN; TRYPSIN; UNCLASSIFIED DRUG; UROKINASE;

ARTICLE; CHEMICAL MODIFICATION; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG EFFICACY; DRUG IDENTIFICATION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; MOLECULE; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

AMIDINES; ANTITHROMBIN III; CRYSTALLOGRAPHY; DRUG DESIGN; ENZYME INHIBITORS; INDOLES; PLASMIN; STRUCTURE-ACTIVITY RELATIONSHIP; THROMBIN; TRYPSIN; URINARY PLASMINOGEN ACTIVATOR;

EID: 0035939251     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00311-0     Document Type: Article

References (12)