Thienopyridines: Nitric oxide synthase inhibitors with potent in vivo activity

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 8, 2001, Pages 1027-1030

  Beaton, Haydn ^a   Boughton Smith, Nigel ^a   Hamley, Peter ^a   Ghelani, Anant ^a   Nicholls, David J ^a   Tinker, Alan C ^a   Wallace, Alan V ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINO 6,7 DIHYDROTHIENO[3,2 C]PYRIDINE; 7 AMINO 4,5 TETRAHYDROTHIENO[2,3 C]PYRIDINE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; THIENO[3,2 C]PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VIVO STUDY; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; BLOOD PRESSURE; CELLS, CULTURED; CEREBELLUM; CYCLOPROPANES; ENZYME INHIBITORS; HUMANS; INHIBITORY CONCENTRATION 50; LIPOPOLYSACCHARIDES; MODELS, ANIMAL; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; OMEGA-N-METHYLARGININE; PYRIDINES; RATS;

EID: 0035938416     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00120-2     Document Type: Article

References (11)