Heterocyclic derivatives of 2-(3,5-dimethylphenyl)tryptamine as GnRH receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 8, 2001, Pages 1077-1080

  Lin, Peter ^a   Parikh, Mamta ^a   Lo, Jane Ling ^a   Yang, Yi Tien ^a   Cheng, Kang ^a   Smith, Roy G ^a   Fisher, Michael H ^a   Wyvratt, Matthew J ^a   Goulet, Mark T ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (3,5 DIMETHYLPHENYL)TRYPTAMINE DERIVATIVE; AMINE; CARBON; GONADORELIN; GONADORELIN ANTAGONIST; HETEROCYCLIC COMPOUND; UNCLASSIFIED DRUG;

ARTICLE; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; RAT;

ANIMALS; BINDING SITES; DRUG DESIGN; FEMALE; HETEROCYCLIC COMPOUNDS; HORMONE ANTAGONISTS; INHIBITORY CONCENTRATION 50; RATS; RECEPTORS, LHRH; TRYPTAMINES;

EID: 0035938412     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00133-0     Document Type: Article

References (7)