Activation of CB1 cannabinoid receptors in rat hippocampal slices inhibits potassium-evoked cholecystokinin release, a possible mechanism contributing to the spatial memory defects produced by cannabinoids

Neuroscience Letters

Volumn 301, Issue 1, 2001, Pages 69-71

  Beinfeld, Margery C ^a   Connolly, Kelly ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cannabinoids; CB1; Cholecystokinin; Spatial memory; WIN 55,212 2

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; CANNABINOID 1 RECEPTOR; CHOLECYSTOKININ; POTASSIUM;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HIPPOCAMPUS; INTERNEURON; LEARNING; MEMORY; NONHUMAN; PRIORITY JOURNAL; RAT; SPATIAL MEMORY;

ANIMALS; CALCIUM CHANNEL BLOCKERS; CANNABINOIDS; CHOLECYSTOKININ; HIPPOCAMPUS; MALE; MEMORY; MORPHOLINES; NAPHTHALENES; POTASSIUM CHLORIDE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CANNABINOID; RECEPTORS, DRUG;

EID: 0035937647     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(01)01591-9     Document Type: Article

References (17)

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3. The distribution of cholecystokinin in the central nervous system of the rat as determined by radioimmunoassay
4. Enhanced long-term potentiation in mice lacking cannabinoid CB1 receptors
5. Cholecystokinin release from the rat caudate-putamen, cortex, and hippocampus is increased by activation of the D1 dopamine receptor
6. Behavioral effects of cannabinoid agents in animals
7. The regulation of cholecystokinin release from rat caudato-putamen in vitro
8. Extra-hippocampal projections of CCK neurons of the hippocampus and subiculum
9. Neuropeptide containing neurons on the cerebral cortex are also GABAergic
10. Presynaptically located CB1 cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneurons
11. Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain
12. Impaired learning and memory in OLETF rats without cholecystokinin (CCK)-A receptor
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14. Rat hippocampal neurons are critically involved in physiological improvement of memory processes induced by cholecystokinin-B receptor stimulation
15. Inhibition of long-term potentiation in rat hippocampal slices by anandamide and WIN55212-2: Reversal by SR141716 A, a selective antagonist of CB1 cannabinoid receptors
16. Cannabinoid CB1 receptors are localized primarily on cholecystokinin-containing GABAergic interneurons in the rat hippocampal formation
17. Cannabinoid ligands and their effects on learning and performance in rhesus monkeys