Phenol derivatives accelerate inactivation kinetics in one inactivation-deficient mutant human skeletal muscle Na+ channel

European Journal of Pharmacology

Volumn 416, Issue 1-2, 2001, Pages 11-18

  Haeseler, Gertrud ^a   Piepenbrink, Alf ^a   Bufler, Johannes ^a   Dengler, Reinhard ^a   Hecker, Hartmut ^a   Aronson, Jeffrey ^b   Piepenbrock, Siegfried ^a   Leuwer, Martin ^c  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Channel inactivation; Phenol derivative; Skeletal muscle

Indexed keywords

4 CHLORO ORTHO CRESOL; 4 CHLOROPHENOL; CHLOROXYLENOL; LIDOCAINE; META CRESOL; MEXILETINE; MUTANT PROTEIN; PHENOL DERIVATIVE; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT; UNCLASSIFIED DRUG;

ARTICLE; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPOLARIZATION; DRUG EFFECT; DRUG STRUCTURE; EMBRYO; GENE; HUMAN; HUMAN CELL; MEMBRANE CURRENT; MUSCLE EXCITATION; MUTATION; MYOTONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKELETAL MUSCLE; THOMSEN DISEASE;

CELL LINE; CHLOROPHENOLS; CRESOLS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; KINETICS; MEMBRANE POTENTIALS; MUSCLE, SKELETAL; MUTATION; PHENOLS; SODIUM CHANNELS; XYLENES;

EID: 0035937582     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(01)00857-3     Document Type: Article

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