Importance of asymmetrical dimethylarginine in cardiovascular risk

Lancet

Volumn 358, Issue 9299, 2001, Pages 2096-2097

  Vallance, Patrick ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DIMETHYLARGININASE; N(G) METHYLARGININE; N(G),N(G) DIMETHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; UREMIC TOXIN;

AGE; AMINO ACID BLOOD LEVEL; AMINO ACID METABOLISM; ATHEROGENESIS; ATHEROSCLEROSIS; CARDIOVASCULAR RISK; CELL ADHESION; CELL FUNCTION; CHRONIC KIDNEY DISEASE; CYTOTOXICITY; DIET SUPPLEMENTATION; DISEASE ASSOCIATION; DISEASE COURSE; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; KIDNEY FAILURE; KIDNEY FUNCTION; METHYLATION; NERVE DEGENERATION; NEUROTRANSMISSION; NOCICEPTION; NOTE; POTASSIUM BLOOD LEVEL; PREDICTION; PREECLAMPSIA; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION; URINARY EXCRETION; VASODILATATION;

EID: 0035936397     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(01)07229-4     Document Type: Note

References (8)

1. The Albert Lasker Medical Research Awards. The discovery of endothelium-derived relaxing factor and its importance in the identification of nitric oxide
2. Accumulation of an endogenous inhibitor of nitric-oxide synthesis in chronic renal failure
3. Biological significance of endogenous methylarginines that inhibit nitric oxide synthases
4. Identification of two human dimethylarginine dimethylaminohydrolases with distinct tissue distributions and homology with microbial arginine deiminases
5. Does ADMA cause endothelial dysfunction?
6. Accumulation of endogenous inhibitors for nitric oxide synthesis and decreased content of L-arginine in regenerated endothelial cells
7. Colocalisation of demethylating enzymes and NOS and functional effects of methylarginines in the kidney
8. Structural insights into the hydrolysis of cellular nitric oxide synthase inhibitors by dimethylarginine dimethylaminohydrolase