Rational design, discovery, and synthesis of a novel series of potent growth hormone secretagogues

Journal of Medicinal Chemistry

Volumn 44, Issue 24, 2001, Pages 4082-4091

  Huang, P ^a   Loew, G H ^a   Funamizu, H ^b   Mimura, M ^b   Ishiyama, N ^b   Hayashida, M ^b   Okuno, T ^b   Shimada, O ^b   Okuyama, A ^b   Ikegami, S ^b   Nakano, J ^b   Inoguchi, K ^b  

^a MOLECULAR RESEARCH INSTITUTE   (United States)

^b KAKEN PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3 AMINO 3 METHYL N [2,3,4,5 TETRAHYDRO 2 OXO 1 [[2' (1H TETRAZOL 5 YL) 1,1' BIPHENYL 4 YL]METHYL] 1H 1 BENZAZEPIN 3 YL]BUTANAMIDE; G 7134; G 7220; GROWTH HORMONE RELEASING FACTOR RECEPTOR; HISTIDYL DEXTRO TRYPTOPHYLALANYLTRYPTOPHYL DEXTRO PHENYLALANYLLYSINAMIDE; IBUTAMOREN; L 164080; PRALMORELIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; DATA BASE; DRUG DESIGN; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HYPOPHYSIS CELL; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAT;

ANIMALS; DATABASES, FACTUAL; DRUG DESIGN; GROWTH HORMONE; MODELS, MOLECULAR; MOLECULAR MIMICRY; PITUITARY GLAND, ANTERIOR; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RATS; THIAZEPINES;

EID: 0035935705     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010207i     Document Type: Article

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