Linearization and integration of DNA into cells preferentially occurs at intrinsically curved regions from human LINE-1 repetitive element

Gene

Volumn 274, Issue 1-2, 2001, Pages 271-281

  Kusakabe, Takahiro ^a   Sugimoto, Yasushi ^b   Maeda, Takuji ^a   Nakajima, Yumiko ^a   Miyano, Masaru ^c   Nishikawa, Jun Ichi ^c   Tone, Shigenobu ^d   Kawaguchi, Yutaka ^a   Koga, Katsumi ^a   Ohyama, Takashi ^c  

^a KYUSHU UNIVERSITY   (Japan)

^b KAGOSHIMA UNIVERSITY   (Japan)

^c KONAN UNIVERSITY   (Japan)

^d TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

Bent DNA; Human LINE 1 element; Retrotransposon integration

Indexed keywords

DNA; DNA FRAGMENT; PLASMID DNA;

ANIMAL CELL; ARTICLE; BACTERIUM; CANCER CELL CULTURE; CELL STRAIN; CHROMOSOME; DNA LIBRARY; DNA SEQUENCE; DNA STRUCTURE; DNA TRANSFECTION; GENE ISOLATION; GENE MAPPING; GENETIC ANALYSIS; HELA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG FIBROBLAST; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REPORTER GENE;

3T3 CELLS; ANIMALS; BASE SEQUENCE; CLONING, MOLECULAR; DNA; DNA RESTRICTION ENZYMES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENOME, HUMAN; HELA CELLS; HUMANS; LONG INTERSPERSED NUCLEOTIDE ELEMENTS; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; NUCLEIC ACID CONFORMATION; PLASMIDS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, NUCLEIC ACID; TRANSFECTION;

EID: 0035934240     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(01)00631-X     Document Type: Article

References (39)

1. Detection, sequence patterns and function of unusual DNA structures
2. A general method for isolation of high molecular weight DNA from eukaryotes
3. Intramolecular DNA triplexes, bent DNA and DNA unwinding elements in the initiation region of an amplified dihydrofolate reductase replicon
4. High-efficiency transformation of mammalian cells by plasmid DNA
5. Revised genomic consensus for the hypermethylated CpG island region of the human L1 transposon and integration sites of full length L1 elements from recombinant clones made using methylation-tolerant host strains
6. LINEs: A superfamily of retrotransposable ubiquitous DNA elements
7. Size and structure of the highly repetitive BAM HI element in mice
8. LINE-1: A mammalian transposable element
9. Human L1 retrotransposon encodes a conserved endonuclease required for retrotransposition
10. Functional replacement of a protein-induced bend in a DNA recombination site
11. Defining the beginning and end of KpnI family segments
12. Sequence-directed curvature of DNA
13. L1 family of repetitive DNA sequences in primates may be derived from a sequence encoding a reverse transcriptase-related protein
14. Bent DNA is a structural feature of scaffold-attached regions in Drosophila melanogaster interphase nuclei
15. Selective cloning and sequence analysis of the human L1 (LINE-1) sequences which transposed in the relatively recent past
16. Bending of DNA by gene-regulatory proteins: Construction and use of a DNA bending vector
17. The sequence of a large L1Md element reveals a tandemly repeated 5′ end and several features found in retrotransposons
18. RNA template requirements for target DNA-primed reverse transcription by the R2 retrotransposable element
19. Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: A mechanism for non-LTR retrotransposition
20. A bent helix in kinetoplast DNA
21. Chromosomal illegitimate recombination in mammalian cells is associated with intrinsically bent DNA elements
22. Identification of an internal cis-element essential for the human L1 transcription and a nuclear factor(s) binding to the element
23. DNA bending creates favored sites for retroviral integration: An explanation for preferred insertion sites in nucleosomes
24. Bent DNA in the human adenovirus type 2 E1A enhancer is an architectural element for transcription stimulation
25. High-efficiency shotgun cloning of curved DNA segments from chromosomal DNA
26. Nucleosomes, DNA-binding proteins, and DNA sequence modulate retroviral integration target site selection
27. Energetic coupling between DNA bending and base pair opening
28. Integration of a vector containing a repetitive LINE-1 element in the human genome
29. Many human L1 elements are capable of retrotransposition
30. Curvature: Software for the analysis of curved DNA
31. Unit-length line-1 transcripts in human teratocarcinoma cells
32. Phasing of protein-induced DNA bends in a recombination complex
33. Hinge-helix formation and DNA bending in various lac repressor-operator complexes
34. Identification, characterization, and cell specificity of a human LINE-1 promoter
35. DNA sequence analysis with a modified bacteriophage T7 DNA polymerase
36. High frequency targeting of genes to specific sites in the mammalian genome
37. The L1Md long interspersed repeat family in the mouse: Almost all examples are truncated at one end
38. A non-curved chicken lysozyme 5′ matrix attachment site is 3′ followed by a strongly curved DNA sequence
39. Gene targeting in normal and amplified cell lines