The Solution Structure of the Complex Formed between α-Bungarotoxin and an 18-mer Cognate Peptide Derived from the α1 Subunit of the Nicotinic Acetylcholine Receptor from Torpedo californica

Journal of Biological Chemistry

Volumn 276, Issue 25, 2001, Pages 22930-22940

  Zeng, Haoyu ^a   Moise, Leonard ^a   Grant, Marianne A ^a,b   Hawrot, Edward ^a  

^a BROWN UNIVERSITY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; NUCLEAR MAGNETIC RESONANCE; POLYPEPTIDES; STOICHIOMETRY;

SOLUTION STRUCTURE;

BIOCHEMISTRY;

ALPHA BUNGAROTOXIN; AMINO ACID; ASPARTIC ACID; CATION; CYSTEINE; LYSINE; NEUROTOXIN; NICOTINIC RECEPTOR; POLYPEPTIDE; PROLINE; PROTON; THREONINE; TYROSINE; VALINE; BUNGAROTOXIN; PEPTIDE;

ALPHA CHAIN; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CALCULATION; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; ELECTRON; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; MUSCLE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; STOICHIOMETRY; STRUCTURE ANALYSIS; TORPEDO CALIFORNICA; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; ISOLATION AND PURIFICATION; MOLECULAR GENETICS; PROTEIN CONFORMATION; SOLUTION AND SOLUBILITY; TORPEDO;

ANIMALIA; TORPEDO; TORPEDO CALIFORNICA;

AMINO ACID SEQUENCE; ANIMALS; BUNGAROTOXINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDES; PROTEIN CONFORMATION; RECEPTORS, NICOTINIC; SOLUTIONS; TORPEDO;

EID: 0035933887     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M102300200     Document Type: Article

References (51)

1. Karlin, A., and Akabas, M. H. (1995) Neuron 15, 1231-1244
2. Antil, S., Servent, D., and Ménez, A. (1999) J. Biol. Chem. 274, 34851-34858
3. Malany, S., Osaka, H., Sine, S. M., and Taylor, P. (2000) Biochemistry 39, 15388-15398
4. Rosenthal, J. A., Levandoski, M. M., Chang, B., Potts, J. F., Shi, Q.-L., and Hawrot, E. (1999) Biochemistry 38, 7847-7855
5. Rosenthal, J. A., Hsu, S. H., Schneider, D., Gentile, L. N., Messier, N. J., Vaslet, C. A., and Hawrot, E. (1994) J. Biol. Chem. 269, 11178-11185
6. Love, R. A., and Stroud, R. M. (1986) Protein Eng. 1, 37-46
7. Basus, V. J., Billeter, M., Love, R. A., Stroud, R. M., and Kuntz, I. D. (1988) Biochemistry 27, 2763-2771
8. Labhardt, A. M., Hunziker-Kwik, E. H., and Wüthrich, K. (1988) Eur. J. Biochem. 177, 295-305
9. Le-Goas, R., LaPlante, S. R., Mikou, A., Delsuc, M. A., Guittet, E., Robin, M., Charpentier, I., and Lallemand, J. Y. (1992) Biochemistry 31, 4867-4875
10. Zinn-Justin, S., Roumestand, C., Gilquin, B., Bontems, F., Ménez, A., and Toma, F. (1992) Biochemistry 31, 11335-11347
11. Connolly, P. J., Stern, A. S., and Hoch, J. C. (1996) Biochemistry 35, 418-426
12. Peng, S.-S., Kumar, T. K. S., Jayaraman, G., Chang, C.-C., and Yu, C. (1997) J. Biol. Chem. 272, 7817-7823
13. Wilson, P. T., Lentz, T. L., and Hawrot, E. (1985) Proc. Natl. Acad. Sci. U. S. A. 82, 8790-8794
14. Grutter, T., Ehret-Sabatier, L., Kotzyba-Hibert, F., and Goeldner, M. (2000) Biochemistry 39, 3034-3043
15. Kachalsky, S. G., Jensen, B. S., Barchan, D., and Fuchs, S. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 10801-10805
16. Wilson, P. T., Hawrot, E., and Lentz, T. L. (1988) Mol. Pharmacol. 34, 643-650
17. Pearce, S. F. A., Preston-Hurlburt, P., and Hawrot, E. (1990) Proc. R. Soc. Lond. Biol. Sci. 241, 207-213
18. Spura, A., Riel, R. U., Freedman, N. D., Agrawal, S., Seto, C., and Hawrot, E. (2000) J. Biol. Chem. 275, 22452-22460
19. Ackermann, E. J., Ang, E. T.-H., Kanter, J. R., Tsigelny, I., and Taylor, P. (1998) J. Biol. Chem. 273, 10958-10964
20. Tomaselli, G. F., McLaughlin, J. T., Jurman, M. E., Hawrot, E., and Yellen, G. (1991) Biophys. J. 60, 721-727
21. Galzi, J. L., Bertrand, D., Devillers-Thiery, A., Revah, F., Bertrand, S., and Changeux, J. P. (1991) FEBS Lett. 294, 198-202
22. Basus, V. J., Song, G., and Hawrot, E. (1993) Biochemistry 32, 12290-12298
23. Kuliopulos, A., and Walsh, C. T. (1994) J. Am. Chem. Soc. 116, 4599-4607
24. Piotto, M., Saudek, V., and Sklenar, V. (1992) J. Biomol. NMR 2, 661-666
25. Sklenar, V., Piotto, M., Leppik, R., and Saudek, V. (1993) J. Magn. Reson. Ser. A 102, 241-245
26. Bodenhausen, G., and Ruben, D. J. (1980) Chem. Phys. Lett. 69, 185-189
27. Bax, A., and Davis, D. G. (1985) J. Magn. Reson. 65, 355-360
28. Davis, A. L., Keeler, J., Laue, E. D., and Moskau, D. (1992) J. Magn. Reson. 98, 207-216
29. Palmer III, A. G., Cavanagh, J., Wright, P. E., and Rance, M. (1991) J. Magn. Reson. 93, 151-170
30. Kay, L. E., Keifer, P., and Saarinen, T. (1992) J. Am. Chem. Soc. 114, 10663-10665
31. Schleucher, J., Sattler, M., and Griesinger, C. (1993) Angew. Chem. Int. Ed. Engl. 32, 1489-1491
32. Vuister, G. W., and Bax, A. (1993) J. Am. Chem. Soc. 115, 7772-7777
33. Vuister, G. W., and Bax, A. (1994) J. Biomol. NMR 4, 193-200
34. Delaglio, F., Grzesiek, S., Vuister, G. W., Zhu, G., Pfeifer, J., and Bax, A. (1995) J. Biomol. NMR 6, 277-293
35. Goddard, T. D., and Kneller, D. G., (2000) SPARKY 3.95, University of California, San Francisco, CA
36. Gentile, L. N., Basus, V. J., Shi, Q.-L., and Hawrot, E. (1995) Ann. N. Y. Acad. Sci. 757, 222-237
37. Bax, A., Vuister, G. W., Grzesiek, S., Delaglio, F., Wang, A. C., Tschudin, R., and Zhu, G. (1994) Methods Enzymol. 239, 79-105
38. Thompson, G. S., Leung, Y.-C., Ferguson, S. J., Radford, S. E., and Redfield, C. (2000) Protein Sci. 9, 846-858
39. Brunger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J.-S., Kuszewski, J., Nilges, N., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Acta Crystallogr. D Biol. Crystallogr. 54, 905-921
40. Rölz, C., and Mierke, D. F. (2001) Biophys. Chem. 89, 119-128
41. Sayle, R. A., and Milner-White, E. J. (1995) Trends Biochem. Sci. 20, 374-376
42. Koradi, R., Billeter, M., and Wüthrich, K. (1996) J. Mol. Graph. 14, 51-55
43. Sobolev, V., Sorokine, A., Prilusky, J., Abola, E. E., and Edelman, M. (1999) Bioinformatics 15, 327-332
44. Gallivan, J. P., and Dougherty, D. A. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 9459-9464
45. Feng, S., Chen, J. K., Yu, H., Simon, J. A., and Schreiber, S. L. (1994) Science 266, 1241-1247
46. Goldenberg, D. P., Koehn, R. E., Gilbert, D. E., and Wagner, G. (2001) Protein Sci. 10, 538-550
47. Scherf, T., Balass, M., Fuchs, S., Katchalski-Katzir, E., and Anglister, J. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 6059-6064
48. Wu, S.-H., Chen, C.-J., Tseng, M.-J., and Wang, K.-T. (1983) Arch. Biochem. Biophys. 227, 111-117
49. Levandoski, M. M., Lin, Y., Moise, L., McLaughlin, J. T., Cooper, E., and Hawrot, E. (1999) J. Biol. Chem. 274, 26113-26119
50. Zhong, W., Gallivan, J. P., Zhang, Y., Li, L., Lester, H. A., and Dougherty, D. A. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 12088-12093
51. Michalet, S., Teixeira, F., Gilquin, B., Mourier, G., Servent, D., Drevet, P., Binder, P., Tzartos, S., Ménez, A., and Kessler, P. (2000) J. Biol. Chem. 275, 25608-25615