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Volumn 66, Issue 19, 2001, Pages 6462-6471

Mechanistic insight into the inactivation of carboxypeptidase A by α-benzyl-2-oxo-1,3-oxazolidine-4-acetic acid, a novel type of irreversible inhibitor for carboxypeptidase A with no stereospecificity

(10) Chung, S J a Chung, S a Hyun Soo Lee, a Kim, E J a Kyung Seok Oh, a Hyuk Soon Choi, a Kim, K S a Yeoun Jin Kim, a Jong Hoon Hahn, a Kim, D H a

a Pohang University of Science and Technology (POSTECH) (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

INACTIVATION;

ACETIC ACID; CATALYSIS; ENZYME INHIBITION; ENZYME KINETICS; ISOMERS; SYNTHESIS (CHEMICAL);

ENZYMES;

ACETIC ACID DERIVATIVE; ALPHA BENZYL 2 OXO 1,3 OXAZOLIDIN 4 ACETIC ACID; ASPARTIC ACID; CARBOXYPEPTIDASE A; ENZYME INHIBITOR; SUCCINIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME BINDING; ENZYME INACTIVATION; ENZYME KINETICS; ENZYME MECHANISM; ENZYME STABILITY; OPTICAL ROTATION; STEREOCHEMISTRY; STEREOISOMERISM; STEREOSPECIFICITY;

CARBOXYPEPTIDASES; CARBOXYPEPTIDASES A; DRUG DESIGN; ENZYME INHIBITORS; HYDROLYSIS; KINETICS; OXAZOLES; PHENYLPROPIONATES; STEREOISOMERISM;

EID: 0035929448 PISSN: 00223263 EISSN: None Source Type: Journal
DOI: 10.1021/jo010421e Document Type: Article

Times cited : (20)

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