Effect of hypothermia on bilirubin-induced alterations in brain cell membrane function and energy metabolism in newborn piglets

Brain Research

Volumn 922, Issue 2, 2001, Pages 276-281

  Park, Won Soon ^a   Chang, Yun Sil ^a   Chung, So Hee ^a   Seo, Dae Won ^a   Hong, Sung Hwa ^a   Lee, Munhyang ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

Bilirubin; Brain protection; Cerebral metabolism; Hypothermia; Newborn piglet

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATE; BILIRUBIN; CREATINE PHOSPHATE; LACTIC ACID; SULFADIMETHOXINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILIRUBIN BLOOD LEVEL; BRAIN CELL; BRAIN DEVELOPMENT; BRAIN INJURY; BRAIN METABOLISM; CELL FUNCTION; CELL MEMBRANE; CONTROLLED STUDY; ENERGY METABOLISM; ENZYME ACTIVITY; INDUCED HYPOTHERMIA; KERNICTERUS; LACTATE BLOOD LEVEL; LIPID PEROXIDATION; NEUROPROTECTION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RECTUM TEMPERATURE; SWINE;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANIMALS, NEWBORN; BILIRUBIN; BLOOD GLUCOSE; BRAIN; CARDIOVASCULAR PHYSIOLOGY; CELL MEMBRANE; CEREBRAL CORTEX; ENERGY METABOLISM; GLUCOSE; HYPOTHERMIA, INDUCED; KERNICTERUS; LACTIC ACID; LIPID PEROXIDATION; NA(+)-K(+)-EXCHANGING ATPASE; NEURONS; PHOSPHOCREATINE; SWINE;

EID: 0035924353     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)03186-9     Document Type: Article

References (38)

1. + transport in canine brain
2. The in vivo effect of bilirubin and sulfisoxazole on cerebral oxygen, glucose, and lactate metabolism in newborn piglets
3. Effect of acidosis on bilirubin deposition in rat brain
4. Determination of conjugated and unconjugated bilirubin by methods based on direct spectrophotometry and chloroform extraction. A reappraisal
5. Binding of bilirubin to albumin
6. Brain bilirubin deposition and brain blood flow during acute urea-induced hyperosmolarity in newborn piglets
7. The neurotoxicity of bilirubin
8. Effect of hyperglycemia on brain cell membrane function and energy metabolism during hypoxia-ischemia in newborn piglets
9. The metabolic effects of mild hypothermia on global cerebral ischemia and recirculation in the cat: Comparison to normothermia and hyperthermia
10. Marked protection by moderate hypothermia after experimental traumatic brain injury
11. Oxidative phosphorylation in experimental bilirubin encephalopathy
12. Post-traumatic brain hypothermia reduces histopathological damage following concussive brain injury in the rat
13. Effect of graded hypoxia on brain cell membrane injury in newborn piglets
14. Comparative aspects of the brain growth spurt
15. Bilirubin-liposome interaction
16. Accurate measurement of cerebral metabolism in the conscious unrestrained neonatal piglet
17. Bilirubin in the brain: Distribution and effects on neurophysiological and neurochemical processes
18. Bilirubin and brain toxicity
19. Defense strategies against hypoxia and hypothermia
20. The in vivo effect of bilirubin on the N-methyl-D-aspartate receptor/ion channel complex in the brains of newborn piglets
21. Hypothermia attenuates excitatory neurotransmitter release in meningitis
22. Hypothermia as an adjunctive treatment for severe bacterial meningitis
23. 31P nuclear magnetic resonance spectroscopy
24. Biochemical alterations in neonatal hyperbilirubinemia and bilirubin encephalopathy: A review
25. Effect of bilirubin on the Arrhenius plots of Na,K-ATPase activities of young and adult rat cerebra
26. Studies on cellular toxicity of bilirubin: Effect on the carbohydrate metabolism in the young rat brain
27. Inhibition of sodium-potassium-ATPase: A potentially ubiquitous mechanism contributing to central nervous system neuropathology
28. Role of glutamate receptor mediated excitotoxicity in bilirubin-induced brain injury in the gunn rat model
29. Effects of bilirubin on mitochondrial reactions
30. Bilirubin: A multi-site inhibitor of mitochondrial respiration
31. Effect of induced hyperglycemia on brain cell membrane function and energy metabolism during the early phase of experimental meningitis in newborn piglets
32. Studies of cellular toxicity of unconjugated bilirubin in kernicteric brain
33. Glucose can fuel glutamate uptake in ischemic brain
34. Post-hypoxic hypothermia reduces cerebrocortical release of NO and excitotoxins
35. Na+, K(+)-ATPase and acetylcholinesterase activities: Changes in postnatally developing rat brain induced by bilirubin
36. 31P nuclear magnetic resonance study in unanesthetized neonatal rats
37. Lipid regulation of cell membrane structure and function
38. Hypothermia and metabolic stress: Narrowing the cellular site of early neuroprotection