Mononuclear platinum(II) complex with 2-phenylpyridine ligands showing high cytotoxicity against mouse sarcoma 180 cells acquiring high cisplatin resistance

Journal of Medicinal Chemistry

Volumn 44, Issue 26, 2001, Pages 4661-4667

  Okada, T ^a   El Mehasseb, I M ^a,b   Kodaka, M ^a   Tomohiro, T ^a   Okamoto, K ^c   Okuno, H ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b TANTA UNIVERSITY   (Egypt)

^c UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 PHENYLPYRIDINE DERIVATIVE; CISPLATIN; GLYCOPROTEIN P; LIGAND; PLATINUM COMPLEX; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG; VERAPAMIL;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CANCER RESISTANCE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG EFFECT; DRUG INHIBITION; DRUG SYNTHESIS; IC 50; MOUSE; NONHUMAN; SARCOMA CELL;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL DIVISION; CISPLATIN; CRYSTALLOGRAPHY, X-RAY; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; FLOW CYTOMETRY; MICE; ORGANOPLATINUM COMPOUNDS; P-GLYCOPROTEIN; PYRIDINES; SARCOMA; TUMOR CELLS, CULTURED; VERAPAMIL;

EID: 0035924233     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010203d     Document Type: Article

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