Identification and characterization of human deoxyguanosine kinase cDNA fragments

Cancer Letters

Volumn 170, Issue 2, 2001, Pages 147-152

  Månsson, Emma ^a   Jönsson, Klas ^a   Albertioni, Freidoun ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

9 D arabinofuranosylguanine; Cladribine; Deoxyguanosine kinase; Mitochondria

Indexed keywords

ANTINEOPLASTIC AGENT; CLADRIBINE; COMPLEMENTARY DNA; DEOXYGUANOSINE KINASE; DEOXYRIBONUCLEOSIDE; DEOXYRIBONUCLEOSIDE TRIPHOSPHATE; DNA FRAGMENT; FLUDARABINE; GUANINE ARABINOSIDE; MESSENGER RNA; NUCLEOSIDE DERIVATIVE; PURINE DERIVATIVE;

ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DNA SEQUENCE; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME PURIFICATION; ENZYME SPECIFICITY; ESCHERICHIA COLI; GENE EXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA CELL; MITOCHONDRION; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION;

BLOTTING, WESTERN; CLONING, MOLECULAR; DNA, COMPLEMENTARY; ESCHERICHIA COLI; HUMANS; LEUKOCYTES, MONONUCLEAR; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RECOMBINANT PROTEINS; TUMOR CELLS, CULTURED;

ARA; ESCHERICHIA COLI;

EID: 0035922180     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(01)00586-9     Document Type: Article

References (10)

1. Substrate specificity of mitochondrial 2′-deoxyguanosine kinase. Efficient phosphorylation of 2-chlorodeoxyadenosine
2. Substrate specificity of human recombinant mitochondrial deoxyguanosine kinase with cytostatic and antiviral purine and pyrimidine analogs
3. Cloning and expression of human mitochondrial deoxyguanosine kinase with cDNA
4. Cloning and expression of human deoxyguanosine kinase cDNA
5. Cloning and characterization of mouse deoxyguanosine kinase. Evidence for a cytoplasmic isoform
6. Apoptosis induces efflux of the mitochondrial matrix enzyme deoxyguanosine kinase
7. Mitochondrial and submitochondrial localization of human deoxyguanosine kinase
8. Expression of deoxycytidine kinase and phosphorylation of 2-chlorodeoxyadenosine in human normal and tumour cells and tissues
9. High incidence of alternatively spliced forms of deoxycytidine kinase in patients with resistant acute myeloid leukemia
10. Elevated expression of multidrug resistance (MDR1) gene upon induction of resistance to 9-β-d-arabinofuranosylguanine (AraG) in human T-lymphoblastic leukemic cells