DMT1 gene expression and cadmium absorption in human absorptive enterocytes

Toxicology Letters

Volumn 122, Issue 2, 2001, Pages 171-177

  Tallkvist, Jonas ^a,b   Bowlus, Christopher L ^c   Lönnerdal, Bo ^b,c  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Absorption; Caco 2; Cadmium; DMT1; Human; Intestine

Indexed keywords

CADMIUM; CARRIER PROTEIN; DIVALENT METAL TRANSPORTER 1 PROTEIN; IRON; UNCLASSIFIED DRUG;

ARTICLE; BASOLATERAL MEMBRANE; CADMIUM POISONING; CATION TRANSPORT; CELL MEMBRANE TRANSPORT; CELL STRAIN CACO 2; CONTROLLED STUDY; CORRELATION FUNCTION; CULTURE MEDIUM; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; INCUBATION TIME; INTESTINE ABSORPTION; INTESTINE CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CADMIUM; CARRIER PROTEINS; CATION TRANSPORT PROTEINS; ENTEROCYTES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INTESTINAL ABSORPTION; IRON; IRON-BINDING PROTEINS; MICE;

EID: 0035918904     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(01)00363-0     Document Type: Article

References (21)

1. Studying transport processes in absorptive epithelia
2. Intestinal absorption of dietary cadmium in women depends on body iron stores and fiber intake
3. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
4. Increased dietary cadmium absorption in mice and human subjects with iron-deficiency
5. Microcytic anemia mice have a mutation in Nramp2, a candidate iron transporter gene
6. Nramp-2 is mutated in the anemic Belgrade (b) rat: Evidence of a role for Nramp-2 in endosomal transport
7. Absorption of iron and chemically related metals in vitro and in vivo: Specificity of the iron binding system in the mucosa of the jejunum
8. Intestinal absorption of heavy metals
9. Interactions between metals in rat jejunum: Implications on the nature of cadmium uptake
10. Health hazards in the manufacture of alkaline accumulators with special reference to chronic cadmium poisoning
11. Developmental patterns of five essential mineral elements in the central nervous system of the fetal and infant guinea pig
12. Cloning and characterization of a mammalian proton-coupled metal-ion transporter
13. Health effects of cadmium exposure - A review of the literature and a risk estimate
14. On the role of metallothionein in cadmium absorption by rat jejunum in situ
15. The human Nramp2 gene: Characterization of the gene structure, alternative splicing, promotor region and polymorphisms
16. In situ hybridization and immunohistochemistry
17. The G185R mutation disrupts function of the iron transporter Nramp-2
18. Functional and molecular responses of human intestinal Caco-2 cells to iron treatment
19. Intestinal absorption of iron and chemically related metals
20. Association between renal effects and cadmium exposure in cadmium-nonpolluted area in Japan
21. Duodenal metal-transporter (DMT1, Nramp-2) expression in patients with hereditary hemochromatosis